Results 11 to 20 of about 8,133 (214)

Human Th17 cells: Are they different from murine Th17 cells? [PDF]

open access: yesEuropean Journal of Immunology, 2009
AbstractType 17 Th (Th17) cells have been identified as a distinct population of CD4+ effector T cells different from Th1 and Th2 cells. While the pre‐eminent cytokine of Th1 cells is IFN‐γ and that of Th2 cells is IL‐4, the distinctive cytokine of Th17 cells is IL‐17A.
ANNUNZIATO, FRANCESCO   +4 more
openaire   +3 more sources

Propionibacterium acnes Promotes Th17 and Th17/Th1 Responses in Acne Patients [PDF]

open access: yesJournal of Investigative Dermatology, 2015
Propionibacterium acnes is a Gram-positive commensal bacterium thought to be involved in the pathogenesis of acne vulgaris. Although the ability of P. acnes in the initiation of pro-inflammatory responses is well documented, little is known about adaptive immune responses to this bacterium.
Kistowska Magdalena   +7 more
openaire   +4 more sources

Expression of the RUNX family in skin lesions from patients with psoriasis vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Objective To explore the expression and distribution of runt-related transcription factor (RUNX) family in lesions of psoriasis vulgaris (PV), and analyze the correlation between its levels and markers of proliferation, apoptosis and immunity.
Dan HONG   +4 more
doaj   +1 more source

Th17 and Allergy

open access: yesAllergology International, 2008
The identification of novel helper T (Th) cell subsets, i.e., IL-17-producing Th cells (Th17 cells) and regulatory T cells (Treg cells), provided new insight into our understanding of the molecular mechanisms involved in the development of infectious and autoimmune diseases as well as immune responses, and thus led to revision of the classic Th1/Th2 ...
Oboki, Keisuke   +3 more
openaire   +2 more sources

Effect of immunocytotherapy on the state of the immune system of women with idiopathic habitual miscarriage

open access: yesМедицинская иммунология, 2020
We aimed  for assessing effects of immunocytotherapy upon  the subpopulations of CD4+CD25highFoxP3+ cellswithnaturalregulatoryactivityandactivatedTh17cellswiththeCD4+CD25highRORγt+ phenotype, as well as in vitro production of cytokines in mitogen ...
L. V. Krechetova   +5 more
doaj   +1 more source

Human Th17 cells [PDF]

open access: yesArthritis Research & Therapy, 2008
The discovery in mice of a new lineage of CD4+ effector T helper (Th) cells that selectively produce IL-17 has provided exciting new insights into immune regulation, host defence, and the pathogenesis of autoimmune and other chronic inflammatory disorders.
openaire   +2 more sources

Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung

open access: yesEuropean Medical Journal Respiratory, 2020
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
doaj   +1 more source

Markers of Th1 polarized Th17 cells (literature review)

open access: yesActa Biomedica Scientifica, 2023
T helpers (Th) producing IL-17 (Th17) have high plasticity and under the influence of external conditions are able to redifferentiate into cells with a different phenotype, primarily in Th1-lymphocytes, forming a population that combines the ...
E. M. Kuklina, N. S. Glebezdina
doaj   +1 more source

Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis

open access: yesMicroorganisms, 2020
Mycobacterium bovis (M. bovis) is a zoonotic pathogen that causes bovine and human tuberculosis. Dendritic cells play a critical role in initiating and regulating immune responses by promoting antigen-specific T-cell activation.
Han Liu   +11 more
doaj   +1 more source

Nuclear transcription factor kB (NF-kB) activity in lymphocyte populations in children with Wilson-Konovalov disease

open access: yesМедицинская иммунология, 2023
Wilson's disease (WD) is a rare hereditary disease caused by a deficiency of the ATF7B transporter. The accumulation of copper can cause damage to organs and cells, mainly the liver.
O. V. Kurbatova   +10 more
doaj   +1 more source

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