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Wilson's disease (WD) is a rare hereditary disease caused by a deficiency of the ATF7B transporter. The accumulation of copper can cause damage to organs and cells, mainly the liver.
O. V. Kurbatova +10 more
doaj +1 more source
Chronic obstructive pulmonary disease (COPD) and lung cancer are global high incidence and high mortality diseases, which seriously increase the socio-economic burden. Smoke exposure, genetic susceptibility and chronic inflammation are common susceptible
Jinhua ZHOU, Wei WANG, Ruijuan LIU
doaj +1 more source
MS is a common disease of the central nervous system that leads to disability and reduced quality of life. The debut of disease in 3-5% of patients occurs in childhood and has a less favorable course compared to adults.
T. V. Radygina +7 more
doaj +1 more source
A rush to judgment on Th17 [PDF]
Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity.
openaire +2 more sources
Th17/Treg Imbalance and Atherosclerosis [PDF]
Atherosclerosis is nowadays recognized as a chronic inflammatory disease of large arteries. In recent years, cellular and molecular biology studies on atherosclerosis confirmed that the occurrence and development are related to inflammation and autoimmunity.
Xin He, Bo Liang, Ning Gu
openaire +2 more sources
Effects of glycodelin on CCR6+ cell subpopulations of Th17-polarized helper T cells
Glycodelins, the glycosylated proteins of reproductive tract are characterized by immunomodulatory functions, are of interest because of their role in the development of immune tolerance.
V. P. Timganova +6 more
doaj +1 more source
Absolute number of stimulated Th17-cells/μl in canine blood with different severity of neurological signs. Green boxplot: Healthy control group; Blue boxplots: IVDH group measured preoperatively, classified by the grading system (grade 1–5) of Sharp and ...
Regina Carlson (388166) +4 more
core +1 more source
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease.
Weshely Kujur +6 more
doaj +1 more source
Dysbiotic microbiota contributes to the pathogenesis of Crohn’s disease (CD) by regulating the immune system. Although pro-inflammatory microbes are probably enriched in the small intestinal (SI) mucosa, most studies have focused on fecal microbiota ...
Manabu Nagayama +20 more
doaj +1 more source
IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M. +5 more
core +1 more source

