Results 31 to 40 of about 163,225 (299)

Nuclear transcription factor kB (NF-kB) activity in lymphocyte populations in children with Wilson-Konovalov disease

open access: yesМедицинская иммунология, 2023
Wilson's disease (WD) is a rare hereditary disease caused by a deficiency of the ATF7B transporter. The accumulation of copper can cause damage to organs and cells, mainly the liver.
O. V. Kurbatova   +10 more
doaj   +1 more source

Research Progress of Treg/Th17 in the Treatment of Chronic Obstructive Pulmonary Disease with Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2019
Chronic obstructive pulmonary disease (COPD) and lung cancer are global high incidence and high mortality diseases, which seriously increase the socio-economic burden. Smoke exposure, genetic susceptibility and chronic inflammation are common susceptible
Jinhua ZHOU, Wei WANG, Ruijuan LIU
doaj   +1 more source

Features of parameters of cellular immune depending on the activity of foci of demyelination in children with multiple sclerosis

open access: yesМедицинская иммунология, 2023
MS is a common disease of the central nervous system that leads to disability and reduced quality of life. The debut of disease in 3-5% of patients occurs in childhood and has a less favorable course compared to adults.
T. V. Radygina   +7 more
doaj   +1 more source

A rush to judgment on Th17 [PDF]

open access: yesThe Journal of Experimental Medicine, 2008
Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity.
openaire   +2 more sources

Th17/Treg Imbalance and Atherosclerosis [PDF]

open access: yesDisease Markers, 2020
Atherosclerosis is nowadays recognized as a chronic inflammatory disease of large arteries. In recent years, cellular and molecular biology studies on atherosclerosis confirmed that the occurrence and development are related to inflammation and autoimmunity.
Xin He, Bo Liang, Ning Gu
openaire   +2 more sources

Effects of glycodelin on CCR6+ cell subpopulations of Th17-polarized helper T cells

open access: yesМедицинская иммунология, 2023
Glycodelins, the glycosylated proteins of reproductive tract are characterized by immunomodulatory functions, are of interest because of their role in the development of immune tolerance.
V. P. Timganova   +6 more
doaj   +1 more source

Th17-cells in comparison of severity grades of dogs suffering from IVDH and the healthy control group.

open access: yes, 2021
Absolute number of stimulated Th17-cells/μl in canine blood with different severity of neurological signs. Green boxplot: Healthy control group; Blue boxplots: IVDH group measured preoperatively, classified by the grading system (grade 1–5) of Sharp and ...
Regina Carlson (388166)   +4 more
core   +1 more source

Caerulomycin A suppresses the differentiation of naïve T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis

open access: yesAutoimmunity, 2017
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease.
Weshely Kujur   +6 more
doaj   +1 more source

TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease

open access: yesGut Microbes, 2020
Dysbiotic microbiota contributes to the pathogenesis of Crohn’s disease (CD) by regulating the immune system. Although pro-inflammatory microbes are probably enriched in the small intestinal (SI) mucosa, most studies have focused on fecal microbiota ...
Manabu Nagayama   +20 more
doaj   +1 more source

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]

open access: yes, 2014
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M.   +5 more
core   +1 more source

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