Results 41 to 50 of about 169,698 (304)

Stimulation of Th17-cells.

open access: yes, 2021
Example of unstimulated Th17-cells (A) and stimulated Th17-cells (B) in canine peripheral blood sample of a dog suffering from intervertebral disc herniation measured by using flow cytometry.
Regina Carlson (388166)   +4 more
core   +1 more source

Immunological considerations in the development of Pseudomonas aeruginosa vaccines

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Pseudomonas aeruginosa is an opportunistic human pathogen capable of causing a wide range of potentially life-threatening infections. With multidrug-resistant P.
Sarah M. Baker   +2 more
doaj   +1 more source

Trypanosomiasis-Induced Th17-Like Immune Responses in Carp [PDF]

open access: yes, 2010
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade   +31 more
core   +2 more sources

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

open access: yesThe Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN   +6 more
doaj   +1 more source

Th17 Cytokines and Barrier Functions [PDF]

open access: yesMediators of Inflammation, 2016
IL-17 functions in host defense against extracellular bacterial and fungal infections and contributes to the pathogenesis of various autoimmune inflammatory diseases. IL-17 producing CD4+ T helper cells (Th17) are a major source of IL-17 in vivo and play a central role in the pathogenesis of autoimmune diseases.
Guansong Wang   +4 more
openaire   +3 more sources

The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer

open access: yesБюллетень сибирской медицины, 2020
The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika   +8 more
doaj   +1 more source

Th17-mediated inflammation in asthma [PDF]

open access: yesCurrent Opinion in Immunology, 2013
Asthma is a heterogeneous disease with many different phenotypes. Moderate and severe asthma phenotypes have been associated with increased neutrophils and increased Th17 cytokines, IL-17A, IL-17F, and IL-22, in the bronchoalveolar lavage fluid of patients.
Dawn C, Newcomb, R Stokes, Peebles
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have
Lázaro Moreira Marques Neto   +7 more
doaj   +1 more source

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