Results 61 to 70 of about 187,124 (359)
Salt-responsive gut commensal modulates TH17 axis and disease
Nature, 2017 A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular disease. High salt may additionally drive autoimmunity by inducing T helper 17 (TH17) cells, which can also contribute to hypertension.
N. Wilck +38 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2019 Innate immunity represents the semi-specific first line of defense and provides the initial host response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive immunity, and both act highly regulated together to establish and ...
K. Bunte, T. Beikler
semanticscholar +1 more source
Th17/Treg Imbalance and Atherosclerosis [PDF]
Disease Markers, 2020 Atherosclerosis is nowadays recognized as a chronic inflammatory disease of large arteries. In recent years, cellular and molecular biology studies on atherosclerosis confirmed that the occurrence and development are related to inflammation and autoimmunity.
Xin He, Bo Liang, Ning Gu
openaire +2 more sources
Th1, Th2, and Th17 cytokines in systemic lupus erythematosus
Autoimmunity, 2020 Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue damage.
Farhana Muhammad Yusoff +2 more
doaj +1 more source
Serum Amyloid A Proteins Induce Pathogenic TH17 Cells and Promote Inflammatory Disease
bioRxiv, 2019 Lymphoid cells that produce IL-17 cytokines protect barrier tissues from pathogenic microbes, but are also prominent effectors of inflammation and autoimmune disease.
June-Yong Lee +17 more
semanticscholar +1 more source
International Journal of Oral Science, 2021 Although mesenchymal stem cell-derived exosomes (MSC-exos) have been shown to have therapeutic effects in experimental periodontitis, their drawbacks, such as low yield and limited efficacy, have hampered their clinical application.
Yong Zhang +9 more
semanticscholar +1 more source
Th17 Cytokines and Barrier Functions [PDF]
Mediators of Inflammation, 2016 IL-17 functions in host defense against extracellular bacterial and fungal infections and contributes to the pathogenesis of various autoimmune inflammatory diseases. IL-17 producing CD4+ T helper cells (Th17) are a major source of IL-17 in vivo and play a central role in the pathogenesis of autoimmune diseases.
Guansong Wang +4 more
openaire +3 more sources
Histopathologic and immunological features of Imiquimod induced psoriatic mouse model
Pifu-xingbing zhenliaoxue zazhi, 2019 Objective: To investigate the dermatopathologic and immunological features of Imiquimod induced psoriatic mice model. Methods: Twenty BALB/c mice were grouped in IMQ-model group and control group randomly, each had 10 mice.
Zhong-zhou HUANG +5 more
doaj +1 more source
Th17-mediated inflammation in asthma [PDF]
Current Opinion in Immunology, 2013 Asthma is a heterogeneous disease with many different phenotypes. Moderate and severe asthma phenotypes have been associated with increased neutrophils and increased Th17 cytokines, IL-17A, IL-17F, and IL-22, in the bronchoalveolar lavage fluid of patients.
Dawn C, Newcomb, R Stokes, Peebles
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source