Results 51 to 60 of about 187,124 (359)
Immunological Medicine, 2022 Th17 cells are implicated in the pathogenesis of several autoimmune diseases. During the inflammation, Th17 cells exposed to IL-12 can shift towards the Th1 phenotype. These shifted cells are defined as ‘non-classic Th1 cells’.
Bo-Young Shin +5 more
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IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease [PDF]
The Journal of Immunology, 2009 Abstract Both IL-23- and IL-1-mediated signaling pathways play important roles in Th17 cell differentiation, cytokine production, and autoimmune diseases. The IL-1R-associated kinase 4 (IRAK4) is critical for IL-1/TLR signaling. We show here that inactivation of IRAK4 kinase in mice (IRAK4 KI) results in significant resistance to ...
Kirk A, Staschke +13 more
openaire +2 more sources
Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism
Acta Medica Bulgarica, 2020 Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
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Journal of Experimental Medicine, 2006 Th17 cells are a distinct lineage of effector CD4+ T cells characterized by their production of interleukin (IL)-17. We demonstrate that Th17 cells also expressed IL-22, an IL-10 family member, at substantially higher amounts than T helper (Th)1 or Th2 ...
Spencer C. Liang +6 more
semanticscholar +1 more source
Features of peripheral blood Treg and Th17 subsets during physiological pregnancy [PDF]
Exploration of ImmunologyAim: Regulatory T (Treg) cells and interleukin-17-producing T helper (Th17) cells play a critical role in successful pregnancy. Treg and Th17 cells differentiate predominantly in the thymus.
Olga Gorbunova +3 more
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Early predictors of efficacy of biological therapy for psoriasis in children
Аллергология и Иммунология в Педиатрии, 2023 .
D. G. Kuptsova +4 more
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Review – Helicobacter: inflammation, immunity and vaccines [PDF]
Microbiota in Health and Disease, 2021 Helicobacter pylori is a bacterium that colonizes the human stomach and is the risk factor for severe gastroduodenal diseases, such as gastric cancer, gastric lymphoma, autoimmune gastritis and peptic ulcer. H.
M. D’Elios, M. de Bernard
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Human gut bacteria produce TH17-modulating bile acid metabolites
bioRxiv, 2021 The microbiota plays a pivotal role in gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17a (TH17 cells).
Donggi Paik +18 more
semanticscholar +1 more source
How to treat a patient with psoriatic arthritis and chronic lymphocytic leukemia? [PDF]
Exploration of Musculoskeletal DiseasesA 76-year-old male patient who has been suffering from psoriatic arthritis (PsA) for 15 years was diagnosed with chronic lymphocytic leukemia (CLL) 18 months ago.
Jürgen Braun +2 more
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IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?
Учёные записки Казанского университета: Серия Естественные науки, 2023 Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
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