Results 21 to 30 of about 169,698 (304)

Th17 effector cells support B bell responses outside of germinal centres [PDF]

, 2012
Th17 cells are pro-inflammatory CD4+T cells, which are important in immune responses against fungal pathogens and extracellular bacteria and have also been implicated in various autoimmune syndromes.
David R Withers, Brewer James M., Benson, RA, David R. Withers, Paola Conigliaro, Agapitos Patakas (120270), Benson, R.A., Iain B McInnes, Patakas, A, David R. Withers (120281), Paul Garside, McInnes Iain B., Paul Garside (21184), Conigliaro, P, Withers, DR, Robert A. Benson, McInnes, I.B., CONIGLIARO, PAOLA, Patakas Agapitos, Benson Robert A., Patakas, A., Conigliaro, P., Withers David R., Agapitos Patakas, Brewer, J.M., Iain B. McInnes (120290), Robert A Benson, Paola Conigliaro (71046), Conigliaro Paola, Garside Paul, Robert A. Benson (120275), Garside, P, Mcinnes, LB, Garside, P., James M. Brewer, Iain B. McInnes, James M Brewer, Withers, D.R., Brewer, JM, James M. Brewer (120295)   +39 more
core   +1 more source

Effect of immunocytotherapy on the state of the immune system of women with idiopathic habitual miscarriage

Медицинская иммунология, 2020
We aimed  for assessing effects of immunocytotherapy upon  the subpopulations of CD4+CD25highFoxP3+ cellswithnaturalregulatoryactivityandactivatedTh17cellswiththeCD4+CD25highRORγt+ phenotype, as well as in vitro production of cytokines in mitogen ...
L. V. Krechetova, V. V. Vtorushina, E. V. Inviyaeva, L. V. Vanko, M. A. Nikolaeva, N. K. Tetruashvili   +5 more
doaj   +1 more source

Human Th17 cells [PDF]

Arthritis Research & Therapy, 2008
The discovery in mice of a new lineage of CD4+ effector T helper (Th) cells that selectively produce IL-17 has provided exciting new insights into immune regulation, host defence, and the pathogenesis of autoimmune and other chronic inflammatory disorders.
openaire   +2 more sources

Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung

European Medical Journal Respiratory, 2020
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
doaj   +1 more source

Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis

Microorganisms, 2020
Mycobacterium bovis (M. bovis) is a zoonotic pathogen that causes bovine and human tuberculosis. Dendritic cells play a critical role in initiating and regulating immune responses by promoting antigen-specific T-cell activation.
Han Liu, Xuekai Xiong, Wenjun Zhai, Tingting Zhu, Xiaojie Zhu, Yifan Zhu, Yongchong Peng, Yongliang Zhang, Jieru Wang, Huanchun Chen, Yingyu Chen, Aizhen Guo   +11 more
doaj   +1 more source

Nuclear transcription factor kB (NF-kB) activity in lymphocyte populations in children with Wilson-Konovalov disease

Медицинская иммунология, 2023
Wilson's disease (WD) is a rare hereditary disease caused by a deficiency of the ATF7B transporter. The accumulation of copper can cause damage to organs and cells, mainly the liver.
O. V. Kurbatova, S. V. Petrichuk, D. G. Kuptsova, G. B. Movsisyan, T. V. Radygina, A. D. Komarova, A. O. Anushenko, E. V. Freidlin, E. L. Semikina, A. S. Potapov, A. P. Fisenko   +10 more
doaj   +1 more source

Th17 cytokines and arthritis [PDF]

Seminars in Immunopathology, 2010
Th17 cells are implicated in human autoimmune diseases, such as rheumatoid arthritis (RA), although it has not been established whether this persistent destructive arthritis is driven by Th1 and/or Th17 cells. Interleukin-17A (IL-17A) contributes to the pathogenesis of arthritis as has been shown in several experimental arthritis models.
openaire   +3 more sources

Immunobiology of IL-17A in human colorectal cancer [PDF]

, 2015
During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
core   +1 more source

Features of parameters of cellular immune depending on the activity of foci of demyelination in children with multiple sclerosis

Медицинская иммунология, 2023
MS is a common disease of the central nervous system that leads to disability and reduced quality of life. The debut of disease in 3-5% of patients occurs in childhood and has a less favorable course compared to adults.
T. V. Radygina, D. G. Kuptsova, O. V. Kurbatova, S. V. Petrichuk, E. L. Semikina, A. P. Fisenko, L. M. Abdullaeva, B. I. Bursagova   +7 more
doaj   +1 more source

A rush to judgment on Th17 [PDF]

The Journal of Experimental Medicine, 2008
Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity.
openaire   +2 more sources