Results 241 to 250 of about 10,689,174 (395)

Demethylation of the RORC2 and IL17A in Human CD4+ T Lymphocytes Defines Th17 Origin of Nonclassic Th1 Cells

Journal of Immunology, 2015
A. Mazzoni, V. Santarlasci, L. Maggi, M. Capone, M. C. Rossi, V. Querci, R. De Palma, Hyun-Dong Chang, A. Thiel, R. Cimaz, F. Liotta, L. Cosmi, E. Maggi, Andreas Radbruch, S. Romagnani, Jun Dong, F. Annunziato   +16 more
semanticscholar   +1 more source

Dampening TH1 cells by Mycobacteria [PDF]

Nature Immunology, 2014
openaire   +2 more sources

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

Unraveling the Microenvironment and the Pathogenic Axis of HIF‐1α–Visfatin–Fibrosis in Autoimmune Pancreatitis Using a Single‐Cell Atlas

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Single‐cell RNA sequencing reveals that type 1 AIP exhibits increased amount and subtypes of B and plasma cells, particularly IgG4+ plasma cells, along with an expansion of Tfh and T helper CD4+ cells. Both AIP types share upregulation of HIF1A+ classical monocytes, which promote pancreatic fibrosis through increased visfatin production.
Deyu Zhang, Congjia Ma, Zhen Wang, Yanfang Liu, Zaoqu Liu, Wanshun Li, Yue Liu, Chang Wu, Liqi Sun, Fei Jiang, Hui Jiang, Xiaoju Su, Lisi Peng, Jiayu Li, Xinyue Wang, Hua Yin, Dongling Wan, Yuyan Zhou, Xiaorong Tian, Shiyu Li, Zhendong Jin, Baoan Ji, Zhaoshen Li, Haojie Huang   +23 more
wiley   +1 more source

Th1 cells are dispensable for primary clearance of Chlamydia from the female reproductive tract of mice. [PDF]

PLoS Pathog, 2022
Rixon JA, Depew CE, McSorley SJ.
europepmc   +1 more source

Interleukin-4-Dependent Immunoglobulin G1 Isotype Switch in the Presence of a Polarized Antigen-Specific Th1-Cell Response to the Trypanosome Variant Surface Glycoprotein

, 1998
Lisa Schopf, Hanna I. Filutowicz, Xiaojuan Bi, John M. Mansfield   +3 more
openalex   +1 more source

Leishmania donovani Infection of a Susceptible Host Results in CD4⁺ T‐Cell Apoptosis and Decreased Th1 Cytokine Production [PDF]

, 1999
Gobardhan Das, H. Vohra, Kanury V. S. Rao, Bhaskar Saha, G. C. Mishra   +4 more
openalex   +1 more source

Liver sinusoidal endothelial cells induce immunosuppressive IL‐10‐producing Th1 cells via the Notch pathway

European Journal of Immunology, 2015
K. Neumann, Christine Rudolph, C. Neumann, M. Janke, D. Amsen, A. Scheffold   +5 more
semanticscholar   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

Exosomal B7-H4 from irradiated glioblastoma cells contributes to increase FoxP3 expression of differentiating Th1 cells and promotes tumor growth. [PDF]

Redox Biol, 2022
Tian Y, Liu C, Li Z, Ai M, Wang B, Du K, Liu W, Wang H, Yu P, Chen C, Lin J, Xu A, Li R, Zhang W, Yuan Y.   +14 more
europepmc   +1 more source