Results 31 to 40 of about 320,868 (298)

Lymphocyte subsets and the role of Th1/Th2 balance in stressed chronic pain patients [PDF]

, 2007
Background: The complex regional pain syndrome (CRPS) and fibromyalgia (FM) are chronic pain syndromes occurring in highly stressed individuals. Despite the known connection between the nervous system and immune cells, information on distribution of ...
Alexander Chouker, Antje Beyer, Avgustin B, Brogden KA, Bruehl S, Buske-Kirschbaum A, Bussone G, Caggiula AR, Christoph Eisner, Elenkov IJ, Gage JR, Geertzen JH, Gilman-Sachs A, Grande LA, Gustav Schelling, Hamaty D, Harden RN, Hennig J, Herbert TB, Hudson JI, Ines Kaufmann, Karlsson H, Kaufmann I, Leone M, Li M, Liblau RS, Maggio M, Manfred Thiel, Marchand F, Marx C, McEwen BS, Milosevic DB, Okada M, Pamuk ON, Peter Richter, Powell JM, Radstake TRDJ, Sacerdote P, Sanders VM, Sarzi-Puttini P, Schinkel C, Schwartzman RJ, Sgoutas-Emch SA, Smart JM, Smyth LJ, Stanton-Hicks M, Stefanski V, Stoll C, Tarcic N, Tournoy KG, Tournoy KG, Tsatsoulis A, Van de Vusse AC, Van Houdenhove B, Van Houdenhove B, Vidovic A, Volker Huge, Walker EA, Weisaeth L, Woiciechowsky C, Yunus MB   +60 more
core   +1 more source

CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

Cell Reports, 2021
Summary: Correct positioning of T cells within infected tissues is critical for T cell activation and pathogen control. Upon tissue entry, effector T cells must efficiently locate antigen-presenting cells (APC) for peripheral activation.
Hen Prizant, Nilesh Patil, Seble Negatu, Noor Bala, Alexander McGurk, Scott A. Leddon, Angela Hughson, Tristan D. McRae, Yu-Rong Gao, Alexandra M. Livingstone, Joanna R. Groom, Andrew D. Luster, Deborah J. Fowell   +12 more
doaj   +1 more source

Retinoic acid as a modulator of T cell immunity [PDF]

, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R., Fernandez, D., Flores-Santibañez, F, Rosemblatt, M., Sauma, D., Tejon, G.   +5 more
core   +1 more source

Imbalance of helper T cell type 1, helper T cell type 2 and associated cytokines in patients with systemic lupus erythematosus: A meta-analysis

Frontiers in Pharmacology, 2022
Objective: Th1 and Th2 cells and their associated cytokines function in the pathogenesis of systemic lupus erythematosus (SLE), but their exact roles are uncertain.
Shate Xiang, Jingjing Zhang, Mengge Zhang, Suhai Qian, Rongyun Wang, Yao Wang, Yingshi Xiang, Xinghong Ding   +7 more
doaj   +1 more source

Kirenol attenuates experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and th17 cells and inducing apoptosis of effector T cells. [PDF]

, 2015
Experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis (MS), is characterized by CNS demyelination mediated by autoreactive T cells.
Deng, Wenbin, Fan, Xiaohang, Liu, Wenwei, Xiao, Juan, Yang, Lin, Yang, Rongbing   +5 more
core   +2 more sources

Increased IFN-γ-producing Th17/Th1 cells and their association with lung function and current smoking status in patients with chronic obstructive pulmonary disease

BMC Pulmonary Medicine, 2019
Background Th17 cells are believed to be important proinflammatory cells in the pathogenesis of chronic obstructive pulmonary disease (COPD). Recent evidence demonstrates that Th17 cells display substantial developmental plasticity, giving rise to Th17 ...
Weihan Xu, Ruimin Li, Yongchang Sun
doaj   +1 more source

Fludarabine Ameliorates Lupus Nephritis by Inhibiting T Cell Infiltration through STAT1 in R848-induced Mice Models

Korean Journal of Clinical Laboratory Science
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease caused by both genetic and environmental factors. Fludarabine is a selective inhibitor of signal transducer and activator of transcription 1 (STAT1). Recently, STAT1 inhibitors have been
Se Gwang JANG
doaj   +1 more source

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation

Frontiers in Immunology, 2020
Memory helper T (Th) cells are crucial for secondary immune responses against infectious microorganisms but also drive the pathogenesis of chronic inflammatory diseases.
Akane S. Suzuki, Ryoji Yagi, Motoko Y. Kimura, Chiaki Iwamura, Kenta Shinoda, Atsushi Onodera, Atsushi Onodera, Kiyoshi Hirahara, Damon J. Tumes, Damon J. Tumes, Ryo Koyama-Nasu, Siiri E. Iismaa, Robert M. Graham, Shinichiro Motohashi, Toshinori Nakayama   +14 more
doaj   +1 more source

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection [PDF]

, 2016
Funding: This work was funded by a Career Development Fellowship (1028634) and a project grant (GRNT1028641) awarded to AHa by the Australian National Health & Medical Research Council (NHMRC).
A Haque, A Haque, A Haque, A Le Bon, A Pratama, A Pratama, A Sabchareon, AJ McAdam, Andreas Hutloff, Ashraful Haque, BC Rocha, Bryce S. Thomas, C Aucan, C Li, C Shin, C Voisine, CC Kim, CG Matar, Christian R. Engwerda, CL Edwards, D Baumjohann, D Liu, D Perez-Mazliah, D Yu, DJ Wikenheiser, DK Raj, DS Karunarathne, DS Khoury, EA Ball, EG Findlay, ES Coro, Fabian de Labastida Rivera, Fernando Souza-Fonseca-Guimaraes, FH Amante, FH Amante, Fiona H. Amante, G Jego, G Suss, G Trinchieri, Geoffrey R. Hill, H Akiba, H Cucak, H Ueno, H Veiga-Fernandes, H Xu, HC van der Heyde, Ismail Sebina, J Banchereau, J Langhorne, J Li, JA Harker, JA Harker, JC Hall, JL Grun, JP Ray, JP Weber, JW Leavenworth, K Warnatz, Kylie R. James, L Beattie, LB Ivashkiv, Lily G. Fogg, Lynette Beattie, Marcela Montes de Oca, Marcela Montes de Oca, Maria M. Mota, Mark J. Smyth, Megan S. F. Soon, MJ Boyle, MT White, N Obeng-Adjei, NS Butler, O Dienz, Paul J. Hertzog, PF Yong, RA Seder, RA Zander, S Cohen, S Crotty, S Nakayamada, S Pichyangkul, S Portugal, S Sharma, Shannon E. Best, T von der Weid, V Ryg-Cornejo, YS Choi, YS Choi, YS Choi, Z Su   +89 more
core   +5 more sources

MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2a as an important regulator of T helper 9 and regularoty T-cell differentiation [PDF]

, 2016
MicroRNAs (miRNAs) regulate many aspects of helper T cell (Th) development and function. Here we found that they are required for the suppression of interleukin‐9 (IL‐9) expression in Th9 cells and other Th subsets. Two highly related miRNAs (miR‐15b and
Baumjohann, Chang, Chong, Clambey, Cobb, Dang, Dardalhon, Elyaman, Filipowicz, Gerlach, Goswami, Goswami, Goswami, Haraguchi, He, Jabeen, Kaelin, Keith, Kohlhaas, Lewis, Licona-Limón, Lu, Lu, Lukashev, McNamee, Muljo, Nakatsukasa, Noelle, Nowak, Pua, Purwar, Schmitt, Shi, Singh, Staudt, Veldhoen, Yao, Zhou   +37 more
core   +2 more sources