Results 41 to 50 of about 4,626,188 (194)
Delayed Activation Kinetics of Th2- and Th17 Cells Compared to Th1 Cells
Cells, 2017 During immune responses, different classes of T cells arise: Th1, Th2, and Th17. Mobilizing the right class plays a critical role in successful host defense and therefore defining the ratios of Th1/Th2/Th17 cells within the antigen-specific T cell ...
Andrea Duechting +3 more
doaj +1 more source
Journal of Neuroinflammation, 2020 Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells).
Julia Loos +7 more
doaj +1 more source
Enhanced Rg3 negatively regulates Th1 cell responses
Journal of Ginseng Research, 2019 Background: Korean Red Ginseng (KRG; Panax ginseng Meyer) is a widely used medicinal herb known to exert various immune modulatory functions. KRG and one of its purified components, ginsenoside Rg3, are known to possess anti-inflammatory activities.
Minkyoung Cho +3 more
doaj +1 more source
Cells, 2012 Experimental allergic encephalomyelitis (EAE) is mediated by neuroantigen-specific pro-inflammatory T cells of the Th1 and Th17 effector class. Th-17 cells can be clearly defined by expression of IL-17, but not IFN-γ, IL-2 or IL-3.
Paul V. Lehmann +3 more
doaj +1 more source
Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]
, 1998 Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Venaille, T.J. +6 more
core
Interferon-β suppresses murine Th1 cell function in the absence of antigen-presenting cells. [PDF]
PLoS ONE, 2015 Interferon (IFN)-β is a front-line therapy for the treatment of the relapsing-remitting form of multiple sclerosis. However, its immunosuppressive mechanism of function remains incompletely understood. While it has been proposed that IFN-β suppresses the
Nicolas Boivin +4 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 ObjectiveThis study aimed to investigate the relationship between intestinal microflora characteristics and the peripheral blood T helper cell (Th)1/Th2 balance in patients with hypothyroidism during the first half of pregnancy.MethodsThe Th1/Th2 ratios ...
Bo Wu +11 more
doaj +1 more source
The role of CD4+T cells in host protective responses against cutaneous Leishmaniasis using genome-wide transcriptomics. [PDF]
, 2013 Includes abstract.Includes bibliographical references.Leishmania major is a protozoan parasite and infection in the human host causes severe cutaneous Leishmaniasis.
Smith, Liezel C
core +1 more source
Wellcome Open Research, 2023 Background CD4+ Th1 cells producing IFN-γ are required to eradicate intracellular pathogens, however if uncontrolled these cells can cause immunopathology.
Marisol Alvarez-Martinez +7 more
doaj +1 more source
The role of Th1 and Th17 cells in glomerulonephritis.
Journal of nephropathology, 2015 T helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not regulated effectively, the autoimmune diseases might develop. The Th17 subset usually produces interleukin-17A which in experimental models of organ-specific autoimmune inflammation is very important.Directory ...
Fatemeh Azadegan-Dehkordi +3 more
openaire +3 more sources