Th2 - Open Access .click

Nature Reviews Immunology, 2017
T helper 2 (TH2) cells orchestrate protective type 2 immune responses, such as those that target helminths and facilitate tissue repair, but also contribute to chronic inflammatory diseases, such as asthma and allergy. Here, we review recent insights into how diverse molecular signals from cellular sources, including dendritic cells, innate lymphoid ...
Jennifer A Walker, A. McKenzie
semanticscholar +3 more sources

Proteases as Th2 adjuvants

Current Allergy and Asthma Reports, 2007
Several cysteine and serine protease allergens have been cloned from house dust mites, including Der p 1, Der p 3, Der p 6, and Der p 9. A significant body of evidence suggests that these allergens mimic helper T (Th) 2 cell adjuvants. Der p 1 cleaves CD23 from activated B cells and CD25 from T cells. Der p 1 proteolytically degrades tight junctions in
Martin D, Chapman, Sabina, Wünschmann, Anna, Pomés +2 more
openaire +2 more sources

Th2 responses in schistosomiasis

Seminars in Immunopathology, 2012
Schistosomiasis is caused by infection with parasitic flatworms of the genus Schistosoma. It is characterized by the development of strong CD4(+) T cell and B cell responses that, during primary infection, fail to eliminate the parasites, but in collaboration with cells of the innate immune system allow survival in the face of ongoing tissue damage ...
Keke, Fairfax +4 more
openaire +2 more sources

immunology
immune system
th2 cells

humans
3. good health
th1

animals
cytokines
internal medicine