Results 61 to 70 of about 4,736,482 (176)

Elevated Th22 Cells Correlated with Th17 Cells in Peripheral Blood of Patients with Acute Myeloid Leukemia

open access: yes, 2014
Acute myeloid leukemia (AML) is a hematological tumor in which progress T helper (Th) subsets including Th22, Th17, and Th1 cells play a pivotal role. However, the role of T helper (Th) subsets in the immune pathogenesis of AML remains unclear.
Chuanfang Liu   +9 more
core   +1 more source

Increased Numbers of Circulating Th22 and Th17 Cells in Children With Kawasaki Disease [PDF]

open access: yes, 2021
Abstract T-helper (Th) 17 and Th22 cells are critical for the pathogenic process of Kawasaki Disease (KD). A total of 43 children with freshly diagnosed KD and 20 healthy controls (HC) were quantified for the numbers of Th17, Th22 and Th1 cells by flow cytometry.
Zhang Liwen   +7 more
openaire   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam   +7 more
wiley   +1 more source

CD4+ cells in autoimmune thyroid disease

open access: yesEndokrynologia Polska, 2021
The phenomenon of autoimmunity develops as a result of the triggering factor released by damaged cells. This leads to an infiltration of CD4+ cells involved in stimulating the effector cells cytotoxicity and stimulating the humoral response.
Szymon Janyga   +5 more
doaj   +1 more source

Correlation between the percentages of Th22 cells as well as Th17 cells and CRP levels as well as DAS28.

open access: yes, 2012
Correlation between the percentages of Th22 cells as well as Th17 cells and CRP levels as well as DAS28.
Lei Qi (173882)   +11 more
core   +1 more source

Th17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only

open access: yesMultiple Sclerosis Journal - Experimental, Translational and Clinical, 2020
Background The nature and extent of inflammation seen in multiple sclerosis (MS) varies throughout the course of the disease. Changes seen in CD4+ T-helper cells in relapsing–remitting (RR) MS and secondary progressive (SP) MS might differ qualitatively ...
S Kalra   +6 more
doaj   +1 more source

Phenotypes and clinical outcomes in children with moderate‐to‐severe atopic dermatitis across diverse ancestries: a Spanish multicenter observational study and cluster analysis (AD‐SKINS Project)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Atopic dermatitis (AD) has a highly variable clinical phenotype and ancestry can contribute to this heterogeneity. This study aims to identify clinical phenotypes of AD in children from diverse ancestry groups, evaluate clinical outcomes and response to treatment, and define phenotypic clusters with potential relevance.
Eugeni Prat‐Colilles   +21 more
wiley   +1 more source

The correlation between the percentages of Th17, Th22 and Th17/Th22 cells in patients.

open access: yes, 2013
The potential correlations among different subsets of CD4+ T cells were analyzed by Spearman rank correlation test. Data shown are the mean values of individual patients (n = 27).
Di Peng (432822)   +4 more
core   +1 more source

TH17 and TH22 cells: A confusion of antimicrobial response with tissue inflammation versus protection [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2012
Substantial progress in understanding mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumors, organ transplantation, chronic infections, and pregnancy is in an exciting developmental phase that might lead to a variety of targeted therapeutic approaches. Recent progress in the interaction between immune/inflammatory cell subsets
Akdis Mübeccel   +4 more
openaire   +4 more sources

Circulating Th22 and Th9 Levels in Patients with Acute Coronary Syndrome

open access: yesMediators of Inflammation, 2013
Background. CD4+ T helper (Th) cells play critical roles in the development and progression of atherosclerosis and the onset of acute coronary syndromes (ACS, including acute myocardial infarction (AMI) and unstable angina pectoris (UAP)). In addition to
Ying-zhong Lin   +9 more
doaj   +1 more source

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