Increased Expressions of IL-22 and Th22 cells in the coxsackievirus B3-Induced mice acute viral myocarditis [PDF]
Virology Journal, 2012 Background Recently, a new subset of T helper (Th) cell that predominantly secret cytokine interleukin-22 (IL-22) is identified, termed Th22 cells. The Th22 subset has been demonstrated to be involved in immunity and tissue inflammation.
Kong Qing +10 more
doaj +2 more sources
A high frequency of circulating th22 and th17 cells in patients with new onset graves' disease. [PDF]
PLoS ONE, 2013 T-helper (Th) 22 and Th17 cells are involved in the pathogenesis of autoimmune diseases. However, their roles in the pathogenesis of Graves'disease (GD) are unclear.
Di Peng +4 more
doaj +2 more sources
Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling. [PDF]
Oncoimmunology, 2016 Th22 cells traffic to and retain in the colon cancer microenvironment, and target core stem cell genes and promote colon cancer stemness via STAT3 and H3K79me2 signaling pathway and contribute to colon carcinogenesis.
Sun D +10 more
europepmc +2 more sources
Circulating Th22 and Th9 Levels in Patients with Acute Coronary Syndrome [PDF]
Mediators of Inflammation, 2013 Background. CD4+ T helper (Th) cells play critical roles in the development and progression of atherosclerosis and the onset of acute coronary syndromes (ACS, including acute myocardial infarction (AMI) and unstable angina pectoris (UAP)). In addition to
Ying-zhong Lin +9 more
doaj +2 more sources
Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome. [PDF]
PLoS ONE, 2012 BackgroundImmunological mechanisms are increasingly recognized in the progression of myelodysplastic syndrome (MDS). Early-stage MDS (E-MDS) is characterized by autoimmune-mediated myelosuppression whereas late-stage MDS (L-MDS) involves immune evasion ...
Lin-lin Shao +11 more
doaj +2 more sources
&bgr;‐Lactam hypersensitivity involves expansion of circulating and skin‐resident TH22 cells [PDF]
Journal of Allergy and Clinical Immunology, 2018 &NA; Figure. No caption available. Background: &bgr;‐Lactam hypersensitivity has been classified according to the phenotype and function of drug‐specific T cells. However, new T‐cell subsets have not been considered.
A. Sullivan +7 more
semanticscholar +6 more sources
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. [PDF]
Journal of Clinical Investigation, 2009 Th subsets are defined according to their production of lineage-indicating cytokines and functions. In this study, we have identified a subset of human Th cells that infiltrates the epidermis in individuals with inflammatory skin disorders and is ...
S. Eyerich +12 more
semanticscholar +4 more sources
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice
Inflammation and RegenerationBackground Thymosin beta family has a significant role in promoting hair regeneration, but which type of T cells play a key role in this process has not been deeply studied.
Nana Tao +7 more
doaj +3 more sources
The Correlation between the Numerical Status of Th22 Cells and Serum Level of IL-22 with Severity of Ulcerative Colitis [PDF]
Iranian Journal of Allergy, Asthma and Immunology, 2018 Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease, yet its etiology as well as pathogenesis remain poorly understood. There is increasing evidence that aberrant expression of CD4+T lymphocytes plays an essential role in the ...
Abbas Arj +4 more
doaj +5 more sources
Th17 and Th22 cells in psoriatic arthritis and psoriasis. [PDF]
Arthritis Res Ther, 2013 Abstract Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin 22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial tissue (ST) in patients with psoriasis (Ps) and psoriatic arthritis (PsA).
Benham H +8 more
europepmc +8 more sources