The Role of T Helper 22 Cells in Dermatological Disorders
Frontiers in Immunology, 2022 T helper 22 (Th22) cells are a newly identified subset of CD4+ T cells that secrete the effector cytokine interleukin 22 (IL-22) upon specific antigen stimulation, barely with IFN-γ or IL-17. Increasing studies have demonstrated that Th22 cells and IL-22
Yu Pan +12 more
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Non-redundant roles for Th17 and Th22 cells in multiple myeloma clinical correlates [PDF]
OncoImmunology, 2016 Maria Pia Protti +2 more
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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals [PDF]
Mucosal Immunology, 2020 International audienceGut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequencies.
M. Nayrac +10 more
semanticscholar +2 more sources
Importance of Th22 Cell Disequilibrium in Immune Thrombocytopenic Purpura [PDF]
Medical Science Monitor, 2018 BACKGROUND The disequilibrium of T helper (Th) cells play an important role in the occurrence and development of immune thrombocytopenic purpura (ITP). Th22 cells, as a newly discovered subset of T lymphocytes, plays an important role in autoimmune disorders and inflammatory diseases.
Zhan, Feng-xia +4 more
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PLoS ONE, 2013 BackgroundAtherosclerosis is a chronic inflammatory disease mediated by immune cells. Th22 cells are CD4(+) T cells that secret IL-22 but not IL-17 or IFN-γ and are implicated in the pathogenesis of inflammatory disease.
Lei Zhang +11 more
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High Frequency of Tc22 and Th22 Cells in Myasthenia Gravis Patients and Their Significant Reduction after Thymectomy [PDF]
Neuroimmunomodulation, 2018 Objectives: Myasthenia gravis (MG) is an autoimmune disease accompanied by a thymic pathology and in most patients thymectomy (TE) is used as the therapeutic approach. Both B and T cells play an important role in MG pathogenesis. Methods: Twelve pre- and
Behrouz Robat-Jazi +7 more
semanticscholar +2 more sources
The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells [PDF]
, 2015 This work was funded by a Cancer Research United Kingdom, Engineering and Physical Sciences Research Council (grant EP/J01771X/1), Medical Research Council and Department of Health England Imaging Programme (MC, MM KD), and by A European Union FAMOS ...
Barbosa, Joao +27 more
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Th22 cells are expanded in multiple sclerosis and are resistant to IFN-β [PDF]
Journal of Leukocyte Biology, 2014 AbstractTh1 and Th17 cells have been considered as effectors in mouse EAE and in the human counterpart, MS. Recently, IL-22, a Th17-related, proinflammatory cytokine, has been associated with a new Th cell subset, defined as Th22, involved in chronic inflammatory conditions, such as psoriasis; the role of IL-22 in MS has not yet been elucidated.
Rolla S +9 more
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Elevated Th22 Cells Correlated with Th17 Cells in Peripheral Blood of Patients with Acute Myeloid Leukemia [PDF]
, 2014 Acute myeloid leukemia (AML) is a hematological tumor in which progress T helper (Th) subsets including Th22, Th17, and Th1 cells play a pivotal role. However, the role of T helper (Th) subsets in the immune pathogenesis of AML remains unclear.
Chuanfang Liu +9 more
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Clinics, 2021 OBJECTIVES: To investigate the efficacy and potential molecular mechanism of Huangkui capsule in combination with leflunomide (HKL) for the treatment of immunoglobulin A nephropathy (IgAN) METHODS: IgAN rat models were constructed by treating rats with ...
Shuwen Pei, Yan Li
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