Circulating Th17, Th22, and Th1 Cells Are Elevated in the Guillain-Barré Syndrome and Downregulated by IVIg Treatments [PDF]
Mediators of Inflammation, 2014 The Guillain-Barré syndrome (GBS) is considered a T helper 1 (Th1) cells-mediated acute inflammatory peripheral neuropathy. However, some changes in GBS could not be explained completely by Th1 cells pathogenic role.
Shujuan Li +6 more
doaj +2 more sources
A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis. [PDF]
Gut, 2015 Objective Helper T (Th) cell responses are critical for the pathogenesis of Helicobacter pylori-induced gastritis. Th22 cells represent a newly discovered Th cell subset, but their relevance to H. pylori-induced gastritis is unknown.
Zhuang Y +22 more
europepmc +8 more sources
The clinical significance of intrahepatic Th22 cells in liver cirrhosis. [PDF]
Advances in Clinical and Experimental Medicine, 2019 BACKGROUND Th22 cells are a recently identified CD4+ T helper subset and have been implicated in the pathogenesis of certain diseases in humans, but the role of Th22 cells in liver cirrhosis (LC) remains unclear.
Shanyu Qin +5 more
semanticscholar +3 more sources
The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia [PDF]
Journal of Immunology Research, 2015 T helper- (Th-) cell immunodeficiency plays important roles in tumor development and their effects in chronic myeloid leukemia (CML) remain unclear.
Ping Chen +7 more
doaj +2 more sources
Changes of circulating Th22 cells in children with hand, foot, and mouth disease caused by enterovirus 71 infection. [PDF]
Oncotarget, 2017 Interleukin (IL)-22+CD4+T (Th22) cells play crucial roles in the pathogenesis of autoimmune diseases and infectious diseases, although the role of Th22 cells remains largely unclear in children with hand, foot, and mouth disease (HFMD) caused by ...
Cui D +14 more
europepmc +2 more sources
HIV impairs and exploits pulmonary Th17 and Th22 cell-mediated immune responses to Mycobacterium tuberculosis. [PDF]
PLoS PathogensTuberculosis (TB) kills an estimated 1.25 million people annually and is the leading cause of death in people with HIV (PWH) (1). The CD4+ T helper (Th) populations play significant roles in protective immunity to Mycobacterium tuberculosis (Mtb) and are
Yazmin B Martinez-Martinez +9 more
doaj +2 more sources
Role of Th22 and IL-22 in pathogenesis of allergic airway diseases: Pro-inflammatory or anti-inflammatory effect? [PDF]
Pediatrics and Neonatology, 2018 A new population of T cells known as Th22 was described for the first time in 2009. These cells are usually identified by the production of IL-22. However, this cytokine is also secreted by other cells such as Th1, Th2, Th17, natural killers, and innate ...
Laura Tamasauskiene +1 more
doaj +2 more sources
Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes. [PDF]
PLoS ONE, 2014 ObjectiveChronic low-grade inflammation has long been recognized as the central link between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22, plays an emerging role in chronic inflammation.
Ruxing Zhao +10 more
doaj +2 more sources
Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells. [PDF]
Inflamm Bowel Dis, 2017 Background: Inflammatory bowel diseases (IBD) are believed to be driven by dysregulated interactions between the host and the gut microbiota. Our goal is to characterize and infer relationships between mucosal T cells, the host tissue environment, and ...
Tang MS +16 more
europepmc +2 more sources
Th22 Cells Contribution in Immunopathogenesis of Rheumatic Diseases
Iranian Journal of Allergy, Asthma and Immunology, 2015 Newly identified T helper cell 22 (Th22) is a subset of CD4+T cells with specific properties apart from other known CD4+ T cell subsets with distinguished gene expression and function.
Gholamreza Azizi +3 more
doaj +2 more sources