The Correlation between the Numerical Status of Th22 Cells and Serum Level of IL-22 with Severity of Ulcerative Colitis [PDF]
Iranian Journal of Allergy, Asthma and Immunology, 2018 Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease, yet its etiology as well as pathogenesis remain poorly understood. There is increasing evidence that aberrant expression of CD4+T lymphocytes plays an essential role in the ...
Abbas Arj +4 more
doaj +3 more sources
PLoS ONE, 2014 ObjectiveChronic low-grade inflammation has long been recognized as the central link between obesity and type 2 diabetes (T2D). The novel subset of T helper (Th) cells, Th22, plays an emerging role in chronic inflammation.
Ruxing Zhao +10 more
doaj +2 more sources
HIV impairs and exploits pulmonary Th17 and Th22 cell-mediated immune responses to Mycobacterium tuberculosis. [PDF]
PLoS PathogensTuberculosis (TB) kills an estimated 1.25 million people annually and is the leading cause of death in people with HIV (PWH) (1). The CD4+ T helper (Th) populations play significant roles in protective immunity to Mycobacterium tuberculosis (Mtb) and are
Yazmin B Martinez-Martinez +9 more
doaj +2 more sources
The role of Th17/Treg balance and Th22 cell in the pathogenesis of DSS-induced colitis in mice
European Journal of Inflammation, 2015 T-helper (Th) cells play a critical role in inflammatory bowel disease (IBD), especially the two new types: Th17 and Th22. But whether they are protective or pathogenic in the gut is still controversial.
Juan Wen +6 more
doaj +2 more sources
European Journal of Inflammation, 2018 The aims of this article are to investigate the effects of Th22 and Th17 cells and plasma cytokines in patients with nonalcoholic fatty liver disease (NAFLD) and to examine the correlation between Th22 and Th17 cells levels and disease progression. Blood
Si-Biao Su +3 more
doaj +2 more sources
Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response [PDF]
Cell ReportsSummary: Neutrophil-derived bactericidal/permeability-increasing protein (BPI) is known for its bactericidal activity against gram-negative bacteria and neutralization of lipopolysaccharide.
Katharina U. Ederer +11 more
core +5 more sources
Circulating Th22 cells, as well as Th17 cells, are elevated in patients with renal cell carcinoma. [PDF]
Int J Med Sci, 2021 T-helper (Th) 22 cells serve an essential role in different types of tumors and autoimmune diseases. No research has been conducted to study the role of Th22 cells in the pathogenesis of renal cell carcinoma (RCC). We aimed to evaluate the prognostic value of circulating Th22, Th17, and Th1 cells in RCC patients. Thirty-two newly diagnosed RCC patients
Peng Z, Hu Y, Ren J, Yu N, Li Z, Xu Z.
europepmc +4 more sources
Recruitment and significance of Th22 cells and Th17 cells in malignant ascites. [PDF]
Oncol Lett, 2018 T helper (Th)22 and Th17 cells are implicated in the pathogenesis of a number of types of cancer. However, the function of Th22 and Th17 cells in malignant ascites (MA) remains unknown. The present study aimed at examining the distribution, phenotypes, recruitment, and prognostic value of Th22 and Th17 cells in MA from patients with hepatocellular ...
Yang XW +5 more
europepmc +4 more sources
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice
Inflammation and RegenerationBackground Thymosin beta family has a significant role in promoting hair regeneration, but which type of T cells play a key role in this process has not been deeply studied.
Nana Tao +7 more
doaj +3 more sources
Effect of methimazole treatment on Th1, Th17, and Th22 lymphocytes in pediatric Graves’ disease patients [PDF]
Frontiers in ImmunologyGraves’ disease is the leading cause of autoimmune hyperthyroidism. Thyroid hormones are an essential element of the endocrine system, playing a pivotal role in the body’s development, especially important in children with intensified growth. Disturbance
Aleksandra Starosz +7 more
doaj +2 more sources