Circulating Th22 cells, as well as Th17 cells, are elevated in patients with renal cell carcinoma. [PDF]
Int J Med Sci, 2021 T-helper (Th) 22 cells serve an essential role in different types of tumors and autoimmune diseases. No research has been conducted to study the role of Th22 cells in the pathogenesis of renal cell carcinoma (RCC).
Peng Z, Hu Y, Ren J, Yu N, Li Z, Xu Z.
europepmc +5 more sources
B cells control lupus autoimmunity by inhibiting Th17 and promoting Th22 cells. [PDF]
Cell Death Dis, 2020 B cells exert immunosuppressive effects and offer therapeutic potential for systemic lupus erythematosus (SLE), but the mechanism remains unclear. Here we analyzed the B cell regulation of Th17/Th22 cell differentiation in lupus and found that α-IgM- and
Yang J, Yang X, Wang L, Li M.
europepmc +5 more sources
Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients [PDF]
Thoracic Cancer, 2023 Background Th22 subset is a particular type of CD4+ T helper cells subset. Our study aimed to explore the expression level of circulating Th22, Th17, Th1, and Th2 cells and the possible mechanism of these cells in breast cancer (BC) with different ...
Zhiguo Peng +9 more
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Recruitment and significance of Th22 cells and Th17 cells in malignant ascites. [PDF]
Oncol Lett, 2018 T helper (Th)22 and Th17 cells are implicated in the pathogenesis of a number of types of cancer. However, the function of Th22 and Th17 cells in malignant ascites (MA) remains unknown.
Yang XW +5 more
europepmc +5 more sources
Current Knowledge of Th22 Cell and IL-22 Functions in Infectious Diseases [PDF]
Pathogens, 2023 T helper 22 (Th22) cells, a newly defined CD4+ T-cell lineage, are characterized by their distinct cytokine profile, which primarily consists of IL-13, IL-22 and TNF-α.
Kunyu Zhang +4 more
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Elevated Th22 cells and related cytokines in patients with epithelial ovarian cancer. [PDF]
Medicine (Baltimore), 2017 This study is conducted to investigate the involvement of T-helper (Th) cells and regulatory T cells in epithelial ovarian cancer (EOC). The percentages of Th22, Th17, Th1, and regulatory T cells in the peripheral blood of EOC patients, benign ovarian ...
Wang T +8 more
europepmc +4 more sources
Th22 cells in allergic disease. [PDF]
Allergo J Int, 2015 During the last decade, the field of T cell immunology started to confuse the scientific community. More and more subtypes of T helper cells and their counterparts in the innate immune system are described. We are just at the beginning to understand which specific function the distinct subtypes fulfill. Th22 cells are terminally differentiated and very
Eyerich K, Eyerich S.
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Downregulation of RUNX3 moderates the frequency of Th17 and Th22 cells in patients with psoriasis. [PDF]
Mol Med Rep, 2016 Psoriasis is a common chronic inflammatory and T cell-meditated skin disease. Runt-related transcription factor 3 (RUNX3), one of the runt-domain family of transcription factors, has been reported to be a susceptibility gene for psoriasis.
Fu D, Song X, Hu H, Sun M, Li Z, Tian Z.
europepmc +5 more sources
Elevated Th22 cells correlated with Th17 cells in patients with high liver stiffness in nonalcoholic fatty liver disease [PDF]
European Journal of Inflammation, 2018 The aims of this article are to investigate the effects of Th22 and Th17 cells and plasma cytokines in patients with nonalcoholic fatty liver disease (NAFLD) and to examine the correlation between Th22 and Th17 cells levels and disease progression. Blood
Si-Biao Su +3 more
doaj +3 more sources
Increased frequency of circulating Th22 cells in patients with B-cell non-Hodgkin's lymphoma. [PDF]
Oncotarget, 2016 T helper (Th) 22 cells play important roles in the pathogenesis of autoimmune and inflammatory diseases, and their function in tumors remains uncertain. In the current study, we investigated the alternations and clinical significance of circulating Th22 ...
Lu T +7 more
europepmc +5 more sources