Results 71 to 80 of about 10,640,595 (395)

Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa

open access: yesFrontiers in Immunology, 2020
Sporotrichosis is a subcutaneous mycotic infection, and Sporothrixglobosa is one of the causative agents with a worldwide distribution, notably in Asia. However, the immune profile in human sporotrichosis caused by S. globosa still remains obscure. Here,
Jianjiao Zu   +7 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

The Stellar Kinematic Center and the True Galactic Nucleus of NGC253 [PDF]

open access: yes, 2010
We present the first sub-arcsecond resolution two-dimensional stellar kinematics and X-ray observations of the prototypical starburst galaxy NGC253 which define the position and nature of the galactic nucleus. We get an estimate of the stellar kinematic center location corresponding to an area of r~1.2" centered 0.7" southwest from the radio core (TH2).
arxiv   +1 more source

Innate Immune Function of TH2 Cells in vivo

open access: yesNature Immunology, 2015
Type 2 helper T cells (TH2 cells) produce interleukin 13 (IL-13) when stimulated by papain or house dust mite extract (HDM) and induce eosinophilic inflammation. This innate response is dependent on IL-33 but not T cell antigen receptors (TCRs).
Liying Guo   +5 more
semanticscholar   +1 more source

CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4. [PDF]

open access: yes, 1993
Type 1 and type 2 cloned T helper (Th) cells are believed to require different antigen-presenting cell (APC)-derived costimuli for proliferation. In the case of Th1-cloned T cells, CD28 signaling costimulates production of autocrine interleukin 2 (IL-2).
McArthur, JG, Raulet, DH
core  

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality [PDF]

open access: yes, 2016
Innate lymphoid cells (ILCs) play key roles in host defense, barrier integrity, and homeostasis and mirror adaptive CD4(+) T helper (Th) cell subtypes in both usage of effector molecules and transcription factors.
Brooks, Stephen R.   +9 more
core   +1 more source

NKG2A inhibits TH2 cell effector function in vitro

open access: yesBMC Pulmonary Medicine, 2007
Background We previously reported that NKG2A, a key inhibitory ligand for HLA-E, is expressed on activated TH2 but not TH1 cells. Here we measured cytokine expression in human ex vivo TH2 cells upon activation with anti-CD3/28 and challenge with an NKG2A-
Mojgani Bahar   +4 more
doaj   +1 more source

Surface activity of cancer cells: the fusion of two cell aggregates [PDF]

open access: yesarXiv, 2021
Although a good comprehension of how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been generated, the impact of collective migration on cellular rearrangement from subcellular to supracellular level remains less understood.
arxiv  

Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing [PDF]

open access: yesPNAS (2017), 2017
When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding to gradients, however, there is a critical difference: even genetically identical cells have differing responses to chemical signals.
arxiv   +1 more source

TH2 cells and their cytokines regulate formation and function of lymphatic vessels

open access: yesNature Communications, 2015
Lymphatic vessels (LVs) are critical for immune surveillance and involved in the pathogenesis of diverse diseases. LV density is increased during inflammation; however, little is known about how the resolution of LVs is controlled in different ...
K. Shin   +6 more
semanticscholar   +1 more source

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