Results 241 to 250 of about 133,879,868 (285)

Enabling tumor-specific drug delivery by targeting the Warburg effect of cancer. [PDF]

open access: yesCell Rep Med
Zhang J   +13 more
europepmc   +1 more source

Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients. [PDF]

open access: yesCancer Res Commun
Subbiah V   +37 more
europepmc   +1 more source

Human tau promotes Warburg effect-like glycolytic metabolism under acute hyperglycemia conditions. [PDF]

open access: yesJ Biol Chem
Yao J   +13 more
europepmc   +1 more source

The Warburg Effect 97 Years After Its Discovery [PDF]

open access: yesCancers, 2020
The deregulation of the oxidative metabolism in cancer, as shown by the increased aerobic glycolysis and impaired oxidative phosphorylation (Warburg effect), is coordinated by genetic changes leading to the activation of oncogenes and the loss of ...
Rosa M Pascale   +2 more
exaly   +3 more sources

The Warburg Effect Revisited—Lesson From the Sertoli Cell

open access: yesMedicinal Research Reviews, 2015
Otto Warburg observed that cancerous cells prefer fermentative instead of oxidative metabolism of glucose, although the former is in theory less efficient.
Marco G. Alves   +2 more
exaly   +2 more sources
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The Warburg effect in 2012

Current Opinion in Oncology, 2012
A revival of interest in tumor metabolism is underway and here we discuss recent results with a focus on the central theme of the Warburg effect, aerobic glycolysis.The M2 tumor-specific isoform of pyruvate kinase has generated much interest, but it has now been reported that PKM2 is not specific to tumors.
Bayley, J.P., Devilee, P.
openaire   +3 more sources

The Warburg Effect: A Signature of Mitochondrial Overload

Trends in Cell Biology, 2023
A long-standing question in cancer biology has been why oxygenated tumors ferment the majority of glucose they consume to lactate rather than oxidizing it in their mitochondria, a phenomenon known as the 'Warburg effect.' An abundance of evidence shows not only that most cancer cells have fully functional mitochondria but also that mitochondrial ...
Gary J Patti
exaly   +3 more sources

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