Results 41 to 50 of about 53,058 (296)

Warburg effect—damping of electromagnetic oscillations [PDF]

open access: yesElectromagnetic Biology and Medicine, 2017
Mitochondrial dysfunction is a central defect in cells creating the Warburg and reverse Warburg effect cancers. However, the link between mitochondrial dysfunction and cancer has not yet been clearly explained. Decrease of mitochondrial oxidative energy production to about 50 % in comparison with healthy cells may be caused by inhibition of pyruvate ...
Jiří, Pokorný   +2 more
openaire   +2 more sources

The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease

open access: yes, 2019
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.

core   +2 more sources

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect. [PDF]

open access: yes, 2015
Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The
Demetrius, L.A.   +2 more
core   +4 more sources

Reversing the Warburg effect to control cancer: a review of diet-based solutions

open access: yesJournal of Current Oncology and Medical Sciences, 2022
Warburg effect is a form of cellular metabolism commonly used by cancer cells, in which, consumption of glucose and production of acidic cell metabolic wastes take place at a considerably higher rate.
Hassan Bahrami   +2 more
doaj  

The Warburg Effect in Diabetic Kidney Disease [PDF]

open access: yesSeminars in Nephrology, 2018
Diabetic kidney disease (DKD) is the leading cause of morbidity and mortality in diabetic patients. Defining risk factors for DKD using a reductionist approach has proven challenging. Integrative omics-based systems biology tools have shed new insights in our understanding of DKD and have provided several key breakthroughs for identifying novel ...
Guanshi, Zhang   +2 more
openaire   +2 more sources

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology

open access: yes, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei   +8 more
core   +1 more source

Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway

open access: yesMolecular Medicine, 2023
Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of
Xu-zhe Fu, Yu Wang
doaj   +1 more source

Synaptic Plasticity and the Warburg Effect [PDF]

open access: yesCell Metabolism, 2014
Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
openaire   +3 more sources

The Reverse Warburg Effect.

open access: yes, 2018
(A-C) Comparison of growth curves from axial simulations of tumor cells between the Warburg effect (WN = 2) and Reverse Warburg effect when 1, 3 and 5 layers of hijacked stromal cells are seeded between the source and tumor cells.
David Dai (457372)   +4 more
core   +1 more source

Genetic Mutations and Non-Coding RNA-Based Epigenetic Alterations Mediating the Warburg Effect in Colorectal Carcinogenesis

open access: yesBiology, 2021
Colorectal cancer (CRC) development is a gradual process defined by the accumulation of numerous genetic mutations and epigenetic alterations leading to the adenoma-carcinoma sequence.
Batoul Abi Zamer   +4 more
doaj   +1 more source

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