Results 31 to 40 of about 133,879,868 (285)
Cell Transplantation, 2021 Energy metabolism programming is a hallmark of cancer, and serves as a potent target of cancer therapy. Valproic acid (VPA), a broad Class I histone deacetylases (HDACs) inhibitor, has been used as a therapeutic agent for cancer.
Zhen Li +7 more
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Frontiers in Cell and Developmental Biology, 2021 Hypoxia reprogrammed glucose metabolism affects the Warburg effect of tumor cells, but the mechanism is still unclear. Long-chain non-coding RNA (lncRNA) has been found by many studies to be involved in the Warburg effect of tumor cells under hypoxic ...
Li Li +4 more
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The reverse warburg effect in osteosarcoma
Oncotarget, 2014 Osteosarcoma is a rare primary malignant tumor of the bone. It is a childhood cancer and has a peak incidence in the second decade of life. Unfortunately, osteosarcoma has a poor prognosis because of its metastatic dissemination to the bone and to the lung.
Federica, Sotgia +2 more
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An Attempt to Reverse Aspects of the Warburg Effect Using 17 β-estradiol
, 2012 A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.The Warburg effect is defined as the propensity for cancer cells to favor glycolysis over ...
Nelson, Vanessa
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Applied SciencesThe Crabtree and Warburg effects both involve elevated glycolytic flux and fermentation under aerobic conditions, yet their regulatory bases differ fundamentally.
Gerardo M. Nava +4 more
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Reversing the Warburg effect to control cancer: a review of diet-based solutions
Journal of Current Oncology and Medical Sciences, 2022 Warburg effect is a form of cellular metabolism commonly used by cancer cells, in which, consumption of glucose and production of acidic cell metabolic wastes take place at a considerably higher rate.
Hassan Bahrami +2 more
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Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
Frontiers in Cell and Developmental Biology, 2018 The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD+, increasing the pool of glycolytic biosynthetic intermediates, and ...
Elizabeth K. Wiese +3 more
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Scientific Reports, 2023 Proliferative diabetic retinopathy (PDR) remains a leading cause of blindness despite progress in screening and treatment. Recently, the Warburg effect, a metabolic alteration affecting amino acid (AA) metabolism in proliferating cells, has drawn ...
Andrew Gregory +7 more
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Molecular Medicine, 2023 Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of
Xu-zhe Fu, Yu Wang
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Synaptic Plasticity and the Warburg Effect [PDF]
Cell Metabolism, 2014 Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
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