Results 31 to 40 of about 53,058 (296)
Cell Death and Disease, 2021 Hypoxic microenvironment is common in solid tumors, particularly in pancreatic ductal adenocarcinoma (PDAC). The Warburg effect is known to facilitate cancer aggressiveness and has long been linked to hypoxia, yet the underlying mechanism remains largely
Rongkun Li +11 more
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Frontiers in Cell and Developmental Biology, 2021 Hypoxia reprogrammed glucose metabolism affects the Warburg effect of tumor cells, but the mechanism is still unclear. Long-chain non-coding RNA (lncRNA) has been found by many studies to be involved in the Warburg effect of tumor cells under hypoxic ...
Li Li +4 more
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The Aurora kinase inhibitor AT9283 inhibits Burkitt lymphoma growth by regulating Warburg effect [PDF]
PeerJ, 2023 Objective To investigate the effect of the kinase inhibitor AT9283 on Burkitt lymphoma (BL) cells and elucidate the underlying mechanisms. Methods The effect of AT9283 on the proliferation of BL cell lines was tested using the MTT assay.
Kaiming Jiang +6 more
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Relevance of the Warburg Effect in Tuberculosis for Host-Directed Therapy
Frontiers in Cellular and Infection Microbiology, 2020 Tuberculosis (TB) was responsible for more deaths in 2019 than any other infectious agent. This epidemic is exacerbated by the ongoing development of multi-drug resistance and HIV co-infection.
Bridgette M. Cumming +4 more
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Cell Transplantation, 2021 Energy metabolism programming is a hallmark of cancer, and serves as a potent target of cancer therapy. Valproic acid (VPA), a broad Class I histone deacetylases (HDACs) inhibitor, has been used as a therapeutic agent for cancer.
Zhen Li +7 more
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Microeconomics of Metabolism: The Warburg Effect as Giffen Behaviour [PDF]
Bulletin of Mathematical Biology, 2021 AbstractMetabolic behaviours of proliferating cells are often explained as a consequence of rational optimization of cellular growth rate, whereas microeconomics formulates consumption behaviours as optimization problems. Here, we pushed beyond the analogy to precisely map metabolism onto the theory of consumer choice.
Jumpei F. Yamagishi +1 more
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The reverse warburg effect in osteosarcoma
Oncotarget, 2014 Osteosarcoma is a rare primary malignant tumor of the bone. It is a childhood cancer and has a peak incidence in the second decade of life. Unfortunately, osteosarcoma has a poor prognosis because of its metastatic dissemination to the bone and to the lung.
Federica, Sotgia +2 more
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Post-translational modifications and the Warburg effect [PDF]
Oncogene, 2013 Post-translational modification (PTM) is an important step of signal transduction that transfers chemical groups such as phosphate, acetyl and glycosyl groups from one protein to another protein. As most of the PTMs are reversible, normal cells use PTMs as a 'switch' to determine the resting and proliferating state of cells that enables rapid and tight
T, Hitosugi, J, Chen
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Applied SciencesThe Crabtree and Warburg effects both involve elevated glycolytic flux and fermentation under aerobic conditions, yet their regulatory bases differ fundamentally.
Gerardo M. Nava +4 more
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Scientific Reports, 2023 Proliferative diabetic retinopathy (PDR) remains a leading cause of blindness despite progress in screening and treatment. Recently, the Warburg effect, a metabolic alteration affecting amino acid (AA) metabolism in proliferating cells, has drawn ...
Andrew Gregory +7 more
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