Results 51 to 60 of about 133,879,868 (285)

Post-translational modifications and the Warburg effect [PDF]

open access: yesOncogene, 2013
Post-translational modification (PTM) is an important step of signal transduction that transfers chemical groups such as phosphate, acetyl and glycosyl groups from one protein to another protein. As most of the PTMs are reversible, normal cells use PTMs as a 'switch' to determine the resting and proliferating state of cells that enables rapid and tight
T, Hitosugi, J, Chen
openaire   +2 more sources

Structural Power Composites Based on High Mass Loading Zn‐Ion Hybrid Supercapacitors with Metal Mesh Current Collectors and Aramid Nanofiber/Glass Fiber Composite Electrolytes

open access: yesAdvanced Functional Materials, EarlyView.
A multifunctional structural power composite is developed by integrating high‐mass‐loading Zn‐ion hybrid supercapacitors with metal mesh current collectors and aramid nanofiber‐based composite electrolytes, enabling simultaneous load‐bearing capability and enhanced areal energy storage.
Yuseung Choi   +8 more
wiley   +1 more source

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α

open access: yesFrontiers in Pharmacology, 2019
The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue.
Xiaoting Hong   +15 more
doaj   +1 more source

Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes. [PDF]

open access: yesPLoS ONE, 2015
Previously we have generated inducible liver tumor models by transgenic expression of Myc or xmrk (activated EGFR homolog) oncogenes in zebrafish. To investigate the interaction of the two oncogenes, we crossed the two transgenic lines and observed more ...
Zhen Li   +4 more
doaj   +1 more source

Uncoupling the Warburg effect from cancer [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
A remarkable trademark of most tumors is their ability to break down glucose by glycolysis at a vastly higher rate than in normal tissues, even when oxygen is copious. This phenomenon, known as the Warburg effect, enables rapidly dividing tumor cells to generate essential biosynthetic building blocks such as nucleic acids, amino acids, and lipids from ...
Najafov, Ayaz, Alessi, Dario R.
openaire   +3 more sources

Rationally designed Warburg effect targeting vector.

open access: yes, 2019
Rationally designed Warburg effect targeting vector.
Alexandra Glenister (6954539)   +2 more
core   +1 more source

Kinetics‐Controlled Architecture of Binder‐Free Organic Electrodes for Enhanced Ion Transport

open access: yesAdvanced Functional Materials, EarlyView.
Pulse reverse electrodeposition controls nucleation and growth to create hierarchically porous Py‐derived oligomeric electrodes with enhanced ionic accessibility and reduced transport resistance. The resulting binder‐free architectures translate these transport advantages into practical sodium‐storage functionality.
Satendra Kumar   +1 more
wiley   +1 more source

An invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathway.

open access: yesPLoS Pathogens, 2014
In this study, we used a systems biology approach to investigate changes in the proteome and metabolome of shrimp hemocytes infected by the invertebrate virus WSSV (white spot syndrome virus) at the viral genome replication stage (12 hpi) and the late ...
Mei-An Su   +15 more
doaj   +1 more source

The Alkaline Diet and the Warburg Effect

open access: yesWorld Nutrition, 2021
The changing diets accompanying our modern life style have increased the content of foods that form acidic metabolic waste residues in the body. Wastes from these metabolic processes are released into the interstitial fluids and the blood, slightly ...
Hassan Bahrami, Ted Greiner
doaj   +1 more source

THE WARBURG EFFECT AND BEYOND [PDF]

open access: yesNeuro-Oncology, 2014
BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2.
openaire   +1 more source

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