Results 71 to 80 of about 133,879,868 (285)

Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer

Cell Death and Disease
The Warburg effect, also known as aerobic glycolysis, plays a crucial role in the onset and progression of colorectal cancer (CRC), although its mechanism remains unclear.
Ruixue Huo, Weihan Li, Hao Wu, Kexin He, Hao Wang, Shan Zhang, Shu-Heng Jiang, Rongkun Li, Junli Xue   +8 more
doaj   +1 more source

CircRNA circ_0008037 facilitates tumor growth and the Warburg effect via upregulating NUCKS1 by binding to miR‐433‐3p in non‐small cell lung cancer

Thoracic Cancer, 2022
Background Circular RNAs (circRNAs) participate in the genesis and progression of tumors, including non‐small cell lung cancer (NSCLC). At present, the role and regulatory mechanisms of circRNAs in NSCLC have not been fully elucidated.
Jia Yu, Haining Zhang, Chunsheng Zhao, Guanghui Li, Yingying Zhang, Yang Sun   +5 more
doaj   +1 more source

The immunological Warburg effect: Can a metabolic‐tumor‐stroma score (MeTS) guide cancer immunotherapy? [PDF]

, 2020
The "glycolytic switch" also known as the "Warburg effect" is a key feature of tumor cells and leads to the accumulation of lactate and protons in the tumor environment.
Kreutz, Marina, Katja Evert, Kathrin Renner, Renner, Kathrin, Evert, Katja, Siska, Peter J., Peter J. Siska, Katrin Singer, Marina Kreutz, Singer, Katrin   +9 more
core   +1 more source

Directional Confinement Governed Ion Transport for Efficient Actuation

Advanced Materials, EarlyView.
Structural anisotropy provides an effective means to regulate ion transport in polymer electrolytes. Directionally aligned channels formed by freeze‐drying provide continuous pathways for ion migration, enhancing ion mobility and simultaneously improving the strain and blocking force of ionic actuators.
Yufei Zhang, Qiuchun Lu, Adit Gupta, Sen Wang, Xueyang Wang, Jian Yu, Xuanyi Hu, Daniel Mandler, Pooi See Lee   +8 more
wiley   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei, Oltvai Zoltán N., Vazquez, A, Zoltán N Oltvai, Alexei Vazquez, Vazquez Alexei, Oltvai, ZN, Oltvai, Zoltán N., Zoltán N. Oltvai   +8 more
core   +2 more sources

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

Advanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar, Timo Weintraut, Sebastian L. Benz, Semih Engün, Sascha Kremer, Anja Henss, Felix H. Richter   +6 more
wiley   +1 more source

Understanding the Warburg Effect

, 2012
This senior integrative exercise explores the current knowledge surrounding the genetic causes and metabolic effects of the Warburg effect in cancer ...
Amaefuna, Steve C.
core   +1 more source

Hippocampal warburg effect mediates hydrogen sulfide-ameliorated diabetes-associated cognitive dysfunction: Involving promotion of hippocampal synaptic plasticity

Neuroscience Research
Our previous studies have reported that hydrogen sulfide (H2S) has ability to improve diabetes-associated cognitive dysfunction (DACD), but the exact mechanisms remain unknown.
Run-Qi Li, Wei-Wen Zhu, Cheng Li, Ke-Bin Zhan, Ping Zhang, Fan Xiao, Jia-Mei Jiang, Wei Zou   +7 more
doaj   +1 more source

Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition

Scientific Reports, 2018
Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its role in affecting cancer metabolism remains poorly understood.
Farid Ahmad Siddiqui, Gopinath Prakasam, Shilpi Chattopadhyay, Asad Ur Rehman, Rayees Ahmad Padder, Mohammad Afaque Ansari, Rasha Irshad, Kailash Mangalhara, Rameshwar N. K. Bamezai, Mohammad Husain, Syed Mansoor Ali, Mohammad Askandar Iqbal   +11 more
doaj   +1 more source

Genetic analysis of the Warburg effect in yeast [PDF]

Advances in Biological Regulation, 2015
We recently discovered that the Warburg effect, defined by the dramatically enhanced metabolism of glucose to pyruvate, even in well-oxygenated cancer cells, can occur as a consequence of mutations that enhance lipid biosynthesis at the expense of respiratory capacity.
Bola, Olayanju, James Jensen, Hampsey, Michael, Hampsey   +2 more
openaire   +2 more sources