Results 11 to 20 of about 133,879,868 (285)

Partners in the Warburg effect [PDF]

open access: yeseLife, 2016
Cells that surround tumors produce vesicles that supply nutrients to cancer cells and, more surprisingly, also impair the generation of energy in these cancer cells.
Joshua D Rabinowitz, Hilary A Coller
doaj   +4 more sources

Mechanism of Warburg Effect and Its Effect on Tumor Metastasis

open access: yesChinese Journal of Lung Cancer, 2015
Cancer cells exhibit altered glucose metabolism characterized by a preference for aerobic glycolysis even when the oxygen content is normal, a phenomenon termed “Warburg effect”. However the definite molecular mechanisms of Warburg effect remains unclear,
Huijun WEI   +4 more
doaj   +2 more sources

Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells

open access: yesDrug Design, Development and Therapy, 2015
Shuai Han,* Shaohua Yang,* Zhai Cai, Dongyue Pan, Zhou Li, Zonghai Huang, Pusheng Zhang, Huijuan Zhu, Lijun Lei, Weiwei Wang Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China ...
Han S   +9 more
doaj   +1 more source

Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer

open access: yesThe Journal of Pathology: Clinical Research, 2022
Previous research has suggested that the expression of proteins related to the Warburg effect may have prognostic value in colorectal cancer (CRC), but results remain inconsistent.
Kelly Offermans   +9 more
doaj   +2 more sources

Reversing the Warburg Effect as a Treatment for Glioblastoma [PDF]

open access: yesJournal of Biological Chemistry, 2013
Glioblastoma multiforme (GBM), like most cancers, possesses a unique bioenergetic state of aerobic glycolysis known as the Warburg effect. Here, we documented that methylene blue (MB) reverses the Warburg effect evidenced by the increasing of oxygen consumption and reduction of lactate production in GBM cell lines.
Ethan, Poteet   +14 more
openaire   +3 more sources

Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer [PDF]

open access: yesBioMed Research International, 2014
Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanisms to a nonoxidative breakdown of ...
González, Claudio Daniel   +5 more
openaire   +4 more sources

Henri Frankfort, Aby Warburg and ‘Mythopoeic Thought’ [PDF]

open access: yes, 2011
This is the text of a lunchtime lecture given at the Warburg Institute in the spring of 2004. It formed part of a series given by current members of staff which were devoted to the work of past Warburg scholars, and was intended to introduce the ...
Taylor, Paul
core   +4 more sources

The Warburg effect: 80 years on [PDF]

open access: yesBiochemical Society Transactions, 2016
Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from that of normal cells. They observed high glucose consumption and large amounts of lactate excretion from cancer cells compared with normal cells, which oxidised glucose using mitochondria.
Morten, K, Potter, M, Newport, E
openaire   +3 more sources

Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect [PDF]

open access: yes, 2011
The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily ...
Tomer Shlomi   +14 more
core   +1 more source

PDGF Promotes the Warburg Effect in Pulmonary Arterial Smooth Muscle Cells via Activation of the PI3K/AKT/mTOR/HIF-1α Signaling Pathway

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: The enhanced proliferation of pulmonary arterial smooth muscle cells (PASMCs) is a central pathological component in pulmonary arterial hypertension (PAH).
Yunbin Xiao   +9 more
doaj   +1 more source

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