Results 31 to 40 of about 5,021 (275)
Supplementary studies on the pharmacological actions of thebaine
A Teraoka
openalex +4 more sources
Drug stability in forensic toxicology
The stability of analytes of interest in solvents and biological matrices depends on many factors, including time, storage conditions, pH, and temperature. It is essential for forensic toxicologists to understand sample preservation techniques and limitations, including analyte metabolism and degradation pathways, when interpreting antemortem and ...
Lorna A. Nisbet+2 more
wiley +1 more source
Opium Alkaloids in Harvested and Thermally Processed Poppy Seeds
The opium alkaloids (morphine, codeine, thebaine, noscapine, and papaverine) have been detected on poppy seeds; they are widely used by the food industry for decoration and flavor but can introduce opium alkaloids into the food chain.
Michelle G. Carlin+2 more
doaj +1 more source
Halophytes have long been used for medicinal purposes. However, their use was entirely empirical, with no knowledge of the bioactive compounds. The plant Tamarix aphylla L. has not drawn the deserving attention for its phytochemical and bioactive explorations, but available data expressed its needs to be attended for its potential.
Sahira A. Aljubouri+2 more
wiley +1 more source
Abstract A laboratory prototype of enzyme biosensor based on pH‐sensitive field‐effect transistors has been created to determine the total content of indole alkaloids in Rauwolfia serpentina tissue culture. Enzyme acetylcholinesterase was immobilized on the surface of pH‐sensitive field‐effect transistors using glutaraldehyde for covalent crosslinking ...
Valentyna Arkhypova+5 more
wiley +1 more source
Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]
The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena+5 more
core +2 more sources
A General Electro‐Synthesis Approach to Amaryllidaceae Alkaloids
Highly pharmaceutically relevant Amaryllidaceae alkaloids have been accessed by a versatile electro‐organic key transformation, including a precursor of the acetylcholinesterase inhibitor galantamine, used as FDA‐approved drug for the treatment of Alzheimer's disease.
Dennis Pollok+4 more
wiley +1 more source
Extraction, radiolabeling, and biodistribution of thebaine in rats [PDF]
The goal of this study was to determine the radiopharmaceutical potential of radioiodinated thebaine. Thebaine was extracted from dry capsules of opium poppy (Papaver somniferum L.), purified using high-performance liquid chromatography, and characterized with nuclear magnetic resonance and infrared spectroscopy.
Enginar, H.+8 more
openaire +3 more sources
Establishment to measure oxycodone in plasma with liquid chromatography–tandem mass spectrometry
Abstract Oxycodone (OXY) is classified as a “strong opioid” in the World Health Organization system of cancer pain treatment. However, OXY also causes severe adverse reactions, such as respiratory depression. Thus, in order to adjust the dosage of OXY for well‐managed pain relief with less toxicity, we tried establishing and validating a system for ...
Suguru Ito+6 more
wiley +1 more source
Background: Papaver bracteatum Lindl. (Persian poppy) has a very long history as the major source of natural alkaloids. Among Papaver species, Persian poppy can be considered as a rich source of thebaine.
Alireza Habibzade+2 more
doaj