Results 61 to 70 of about 5,570 (173)

Extracellular proteolytic enzymes produced by human pathogenic Vibrio species

open access: yesFrontiers in Microbiology, 2013
Bacteria in the genus Vibrio produce extracellular proteolytic enzymes to obtain nutrients via digestion of various protein substrates. However, the enzymes secreted by human pathogenic species have been documented to modulate the bacterial virulence ...
Shin-Ichi eMiyoshi
doaj   +1 more source

Current Overview and Main Challenges of the Use of Galleria mellonella in Biomedical Research

open access: yesCurrent Protocols, Volume 6, Issue 4, April 2026.
Abstract Larvae of the greater wax moth Galleria mellonella have become an increasingly important in vivo model for biomedical research, providing a practical, ethical, and biologically relevant alternative to vertebrate organisms. Its suitability as a model system lies in its low maintenance cost, ease of handling, and ability to survive at both ...
Fabiana Alves de Souza Silva   +11 more
wiley   +1 more source

Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
M.A.S. Medeiros   +4 more
doaj   +1 more source

The Japanese Macaque as a Diabetes Recipient Animal Model for Porcine Islet Xenotransplantation

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Porcine islet xenotransplantation is effective for severe diabetes; however, preclinical studies are essential. In this study, we evaluated the suitability of the Japanese macaque as a recipient model for islet xenotransplantation, including identifying the preferred method to induce diabetes.
Naoaki Sakata   +4 more
wiley   +1 more source

Antioxidant Activity of Purified Active Peptide Derived from Spirulina platensis Enzymatic Hydrolysates

open access: yesResearch Journal of Life Science, 2017
The aim of this study is to isolate the antioxidative peptide from Spirulina platensis. Peptide was obtained by proteolytic digestion, ultrafiltration, fractionation by RP-HPLC, identified by LC-MS/MS—MASCOT Distiller and measured its antioxidant ...
Nur Maulida Safitri   +2 more
doaj   +1 more source

The synthesis of optically enriched 2-benzyl- 3-nitropropionic amide

open access: yesGreen Processing and Synthesis, 2015
The present communication describes a valuable procedure for the short and facile synthesis of a thermolysin inhibitor, i.e. optically enriched 2-benzyl-3-nitropropionic amide, successfully synthesized by virtue of a diastereoisomeric mixture ...
Wang Si-Hong, Yin Xiu-Mei
doaj   +1 more source

High-resolution mass spectrometry driven discovery of peptidic danger signals in insect immunity.

open access: yesPLoS ONE, 2013
The 'danger model' is an alternative concept for immune response postulating that the immune system reacts to entities that do damage (danger associated molecular patterns, DAMP) and not only to entities that are foreign (pathogen-associated molecular ...
Arton Berisha   +4 more
doaj   +1 more source

Angiotensin I Converting Enzyme Inhibitory Peptides Derived from Phycobiliproteins of Dulse Palmaria palmata

open access: yesMarine Drugs, 2016
We examined the inhibitory activity of angiotensin I converting enzyme (ACE) in protein hydrolysates from dulse, Palmaria palmata. The proteins extracted from dulse were mainly composed of phycoerythrin (PE) followed by phycocyanin (PC) and ...
Tomoe Furuta   +4 more
doaj   +1 more source

Purification and biochemical characterization of a novel thermostable protease from the oyster mushroom Pleurotus sajor-caju strain CTM10057 with industrial interest

open access: yesBMC Biotechnology, 2019
Background Proteases are hydrolytic enzymes that catalyze peptide linkage cleavage reactions at the level of proteins and peptides with different degrees of specificity. This group draws the attention of industry.
Maroua Omrane Benmrad   +8 more
doaj   +1 more source

Probing Conformational Feature of a Recombinant Pyruvate Kinase by Limited Proteolysis [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2013
Pyruvate kinase is a key enzyme in glycolytic pathway that catalyzes the transphosphorylation between phosphoenolpyruvate and ADP to yield ATP and Pyruvate.
M. Banijamali   +2 more
doaj  

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