Results 11 to 20 of about 26,404 (254)

Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold

open access: yesChemistry, 2022
The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities.
Tulika Anthwal   +2 more
doaj   +1 more source

Synthesis of some Schiff's bases derivatives from aminoazo compounds

open access: yesمجلة بغداد للعلوم, 2007
Reaction of,2- [( 4- amio phenyl ) diazenyl] 1,3,4- thiadiazole -5- thiol (S1) with p- chlorobenzeldehyde,3,4 – dimethoxy benzaldehyde and pyrrol-2- carbonxaldehyde gave -5- [{4-(4-chlorobenzylidene amino) phenyl} diezenyl]-1,3,4- thiadiazole-2- thiol ...
Baghdad Science Journal
doaj   +1 more source

Corrosion Inhibition Effect of Substituted Thiadiazoles on Brass

open access: yesInternational Journal of Electrochemical Science, 2011
The corrosion inhibition of thiadiazole derivatives for brass in natural seawater has been evaluated by potentiodynamic polarisation and electrochemical impedance spectroscopic techniques.
X. Joseph Raj, N. Rajendran
doaj   +1 more source

Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds

open access: yesMolecules, 2022
New 1,3,4-thiadiazole thioglycosides linked to a substituted arylidine system were synthesized via heterocyclization via click 1,3-dipolar cycloaddition.
Hussein H. Elganzory   +5 more
doaj   +1 more source

In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity [PDF]

open access: yes, 2019
The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin-tetrazolyl and -thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of ...
Andrade, Joana M.   +9 more
core   +1 more source

Synthesis and Characterization of Five, Sevene Heterocyclic Membered Rings

open access: yesمجلة بغداد للعلوم, 2013
New compounds containing heterocyclic units have been synthesized. These compounds include 2-amino 5- phenyl-1,3,4-thiadiazole (1) as starting material to prepare the Schiff bases 2N[3-nitrobenzylidene -2 hydroxy benzylidene and 4-N,N-dimethyl ...
Baghdad Science Journal
doaj   +1 more source

Synthesis, Characterization and Single Crystal X-ray Diffraction Analysis of Fused Triazolo/Thiadiazole Clubbed with Indole Scaffold

open access: yesCrystals, 2023
The present synthetic strategy involves the synthesis of indolyl-triazolo-thiadiazole heterocyclic ring systems 8–13 from the condensation of 4-amino-5-(1H-indol-2-yl)-3H-1,2,4-triazole-3-thione 1 with the aromatic carboxylic acid derivatives 2–7 in ...
Mezna Saleh Altowyan   +7 more
doaj   +1 more source

Preparation of some azo compounds by diazotization and coupling of 2- amino -5 – thiol -1,3,4- thiadizaole

open access: yesمجلة بغداد للعلوم, 2015
2- amino -5- thiol-1,3,4- thiadiazole (S1) was prepared by cyclic locking of thiosemicarbazide in the presence of anhydrous sodium carbonate and CS2. diazotization of (S1) compound gave diazonium salt (S2) that reacts with different activated aromatic ...
Baghdad Science Journal
doaj   +1 more source

Synthesis and Bioactivities of Novel 1,3,4-Thiadiazole Derivatives of Glucosides

open access: yesFrontiers in Chemistry, 2021
A series of novel 1,3,4-thiadiazole derivatives of glucosides were synthesized by the starting materials d-glucose and 5-amino-1,3,4-thiadiazole-2-thiol in good yields with employing a convergent synthetic route.
Meihang Chen   +7 more
doaj   +1 more source

Inductive queries for a drug designing robot scientist [PDF]

open access: yes, 2010
It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that ...
A. Lingas   +10 more
core   +1 more source

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