Results 111 to 120 of about 67,735 (340)

Aggregation, Photoluminescence, and Cytotoxicity of Pt(II) and Re(I) Complexes Bearing Multimodal‐Coordinating Luminophores

open access: yesChemistry – A European Journal, EarlyView.
A polydentate ligand with multiple coordination patterns (bidentate N*N‐mode for Pt(II) and Re(I) centers, tridentate C^N*N‐motive for Pt(II)‐based complexes) is herein presented. The attained coordination‐chemical versatility in combination with different co‐ligands was employed to achieve sophisticated structural features and tunable photophysical ...
Stefan Buss   +10 more
wiley   +1 more source

Thiazole, triazole, thio- and semicarbazone derivatives - Promising moieties for drug development for the treatment of tuberculosis

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2021
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB).
Cauê Benito Scarim   +1 more
doaj  

Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

open access: yesMolecules, 2007
A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis.
George W. Weaver   +4 more
doaj   +1 more source

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation [PDF]

open access: yes, 2009
In 2004, we used NMR to solve the structure of the minor groove binder thiazotropsin A bound in a 2 : 1 complex to the DNA duplex, d(CGACTAGTCG)2. In this current work, we have combined theory and experiment to confirm the binding thermodynamics of this ...
Alniss, Hasan   +9 more
core   +1 more source

A ketol‐acid reductoisomerase inhibitor that has antituberculosis and herbicidal activity.

open access: yesChemistry – A European Journal, Accepted Article.
Ketol‐acid reductoisomerase (KARI) is a target for the development of new biocidal agents. This is based on its essential role in branched chain amino acid biosynthesis in plants and microorganisms, and its absence in animals. The lack of success in developing KARI inhibitors as biocides may be because the inhibitors assessed to date compete directly ...
Luke William Guddat   +9 more
wiley   +1 more source

Uses of Anthranilic Acid for the Synthesis of Dihydroquinazolin Derivatives with Antitumor, Anti-proliferative and Pim-1kinase Activities

open access: yesActa Chimica Slovenica, 2018
The reaction of anthranilic acid with ethoxycarbonylisothiocyanate gave the ethyl 4-oxo-2-thioxo-1,2-dihydroquinazoline-3(4H)-carboxylate (4). The reaction of compound 4 with hydrazine hydrate and a-halocarbonyl derivatives was found to give either ...
Rafat M. Mohareb, Peter A. Halim
doaj   +1 more source

Thiazolo[5,4-d]thiazole-based organic sensitizers with improved spectral properties for application in greenhouse-integrated dye-sensitized solar cells

open access: yesSustainable Energy & Fuels, 2020
Semitransparent dye-sensitized solar cells (DSSCs) for greenhouse integration were manufactured by using especially designed organic dyes featuring different heterocyclic moieties integrated into a thiazolo[5,4-d]thiazole-molecular scaffold.
A. Dessì   +11 more
semanticscholar   +1 more source

On the Importance of Balancing the pKa of the Additive in β‐Ketoenamine COF Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Due to the irreversible tautomerization of imine linkages to their corresponding ketoenamines, β‐ketoenamine‐linked Covalent Organic Frameworks (COFs) are a stable type of COF that displays high surface areas. In the solvothermal synthesis of such COFs, the use of (acetic) acid is ubiquitous. However, the effect of the added acid on the COF properties (
Thijmen A. van Voorthuizen   +3 more
wiley   +1 more source

Synthesis and Biological Activity of 3-[Phenyl(1,3-thiazol-2-yl)-amino]propanoic Acids and Their Derivatives

open access: yesMolecules, 2013
New N,N-disubstituted β-amino acids and their derivatives with thiazole, aromatic, and heterocyclic substituents were synthesized from N-phenyl-N-thiocarbamoyl-β-alanine by the Hantzsch method; derivatives with hydrazone fragments were also obtained ...
Vytautas Mickevičius   +8 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of 4-(naphthalen-2-yl)-N-[(Z)-4-propoxybenzylidene]-1,3-thiazol-2-amine

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
The asymmetric unit of the title compound, C23H20N2OS, contains one slightly bent molecule. The naphthalene ring system and the thiazole ring are twisted with respect to each other, making a dihedral angle of 13.69 (10)°; the anisole ring is inclined to ...
Ropak A. Sheakh Mohamad   +2 more
doaj   +1 more source

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