Results 31 to 40 of about 424,053 (243)
The matching of a “one-dimensional” numerical simulation and experiment results for low viscosity Newtonian and non-Newtonian fluids during fast filament stretching and subsequent break-up [PDF]
, 2012 This paper develops a model for fast filament stretching, thinning, and break-up for Newtonian and non-Newtonian fluids, and the results are compared against experimental data where fast filament relaxation occurs. A 1D approximation was coupled with the
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Thick-film Piezoceramic Microgenerators [PDF]
, 2008 Piezoelectric materials have many desirable characteristics for use in vibration energy harvesting applications. They can produce relatively high output voltages (from a few to several tens of volts) for modest levels of vibration.
White, N. M., Kok, S. L., Harris, N. R.
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The ubiquitin ligase Ozz decreases the replacement rate of embryonic myosin in myofibrils
Physiological Reports, 2021 Myosin, the most abundant myofibrillar protein in skeletal muscle, functions as a motor protein in muscle contraction. Myosin polymerizes into the thick filaments in the sarcomere where approximately 50% of embryonic myosin (Myh3) are replaced within 3 h
Emi Ichimura +5 more
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Applied Sciences, 2022 Femtosecond laser filament-generated plasma can generate electromagnetic pulses (EMPs). These pulses may reduce the instrument’s precision, and, hence, influence the accuracy of the experimental results.
Rong Qi +8 more
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eLife, 2017 The Frank-Starling relation is a fundamental auto-regulatory property of the heart that ensures the volume of blood ejected in each heartbeat is matched to the extent of venous filling. At the cellular level, heart muscle cells generate higher force when
Xuemeng Zhang +5 more
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Bioengineering, 2022 Dense collagen hydrogels are promising biomaterials for several tissue-engineering applications. They exhibit high mechanical properties, similar to physiological extracellular matrices, and do not shrink under cellular activity.
Marie Camman +4 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
BMC Cell Biology, 2010 Background Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and biochemical studies in C. elegans have demonstrated that Unc-45 facilitates the process of myosin folding and assembly in body wall ...
Zhang Pei-Jun +2 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Relation Between the Mechanical Properties of Muscles and Their Structure on the Molecular Level
Engineering Transactions, 2015 Mechanical properties of the vertebrate skeletal muscles are satisfactorily described on the basis of a new model of the myosin molecule packing into the thick filament.
L. Skubiszak, L. Kowalczyk
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