Results 41 to 50 of about 424,053 (243)
Patterned crack-free PZT thick films for micro-electromechanical system applications [PDF]
, 2007 The fabrication and structuring of multilayer-thick film piezoelectric (PZT-lead zirconate titanate) structures, using composite sol-gel techniques and wet etching is described.
F. Dauchy +5 more
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations
Stem Cell Reports, 2019 Summary: Thick-filament sarcomere mutations are a common cause of hypertrophic cardiomyopathy (HCM), a disorder of heart muscle thickening associated with sudden cardiac death and heart failure, with unclear mechanisms.
Rachel Cohn +10 more
doaj +1 more source
Thick-Filament Extensibility in Intact Skeletal Muscle [PDF]
Biophysical Journal, 2018 Myofilament extensibility is a key structural parameter for interpreting myosin cross-bridge kinetics in striated muscle. Previous studies reported much higher thick-filament extensibility at low tension than the better-known and commonly used values at high tension, but in interpreting mechanical studies of muscle, a single value for thick-filament ...
Weikang, Ma +5 more
openaire +2 more sources
Thick Filament Length and Isoform Composition Determine Self-Organized Contractile Units in Actomyosin Bundles [PDF]
, 2013 International audienceDiverse myosin II isoforms regulate contractility of actomyosin bundles in disparate physiological processes by variations in both motor mechanochemistry and the extent to which motors are clustered into thick filaments.
Thoresen, Todd +4 more
core +1 more source
Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing [PDF]
, 2021 Myosin-based regulation in the heart muscle modulates the number of myosin motors available for interaction with calcium-regulated thin filaments, but the signaling pathways mediating the stronger contraction triggered by stretch between heartbeats or by
Park-Holohan, So Jin +5 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Cells, 2023 As an essential component of the sarcomere, actin thin filament stems from the Z-disk extend toward the middle of the sarcomere and overlaps with myosin thick filaments. Elongation of the cardiac thin filament is essential for normal sarcomere maturation
Reiri Sono +18 more
doaj +1 more source
Two-photon excited LIF determination of H-atom concentrations near a heated filament in a low pressure H2 environment [PDF]
, 1990 Meier U, Kohse-Höinghaus K, Schäfer L, Klages C-P. Two-photon excited LIF determination of H-atom concentrations near a heated filament in a low pressure H2 environment. Applied Optics.
Kohse-Höinghaus, Katharina +3 more
core
Modeling crossbridge structure of the frog skeletal thick myosin filament.
, 2013 (A) Distributions of the perturbed region (blue), the regular region (green) of myosin crossbridge arrays and the C-protein region (red) along the thick filament in resting frog muscles.
Thomas C. Irving (293205) +3 more
core +1 more source