Results 41 to 50 of about 125,465 (286)

The dynamical state of the First Hydrostatic Core Candidate Cha-MMS1 [PDF]

open access: yes, 2013
Observations of First Hydrostatic Core candidates, a theoretically predicted evolutionary link between the prestellar and protostellar phases, are vital for probing the earliest phases of star formation.
Belloche, A.   +3 more
core   +3 more sources

Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos

open access: yesBMC Cell Biology, 2010
Background Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and biochemical studies in C. elegans have demonstrated that Unc-45 facilitates the process of myosin folding and assembly in body wall ...
Zhang Pei-Jun   +2 more
doaj   +1 more source

Light Filaments Without Self Guiding [PDF]

open access: yes, 2003
An examination of the propagation of intense 200 fs pulses in water reveals light filaments not sustained by the balance between Kerr-induced self-focusing and plasma-induced defocusing. Their appearance is interpreted as the consequence of a spontaneous
A. Braun   +12 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Relation Between the Mechanical Properties of Muscles and Their Structure on the Molecular Level

open access: yesEngineering Transactions, 2015
Mechanical properties of the vertebrate skeletal muscles are satisfactorily described on the basis of a new model of the myosin molecule packing into the thick filament.
L. Skubiszak, L. Kowalczyk
doaj   +1 more source

Production of a short-lived filament by a surge [PDF]

open access: yes, 1976
A large surge was observed on September 17, 1971 part of which, after travelling 200,000 km across the surface, returned to the surface to form a filament. The filament lasted about 30 minutes, then rose up and returned to the source of the surge.
Zirin, H.
core   +1 more source

Magnetic fields of an active region filament from full Stokes analysis of Si I 1082.7 nm and He I 1083.0 nm

open access: yes, 2012
Vector magnetic fields of an active region filament in the photosphere and upper chromosphere are obtained from spectro-polarimetric observations recorded with the Tenerife Infrared Polarimeter (TIP II) at the German Vacuum Tower Telescope (VTT).
A. Lagg   +26 more
core   +1 more source

Simulation and analysis of solenoidal ion sources [PDF]

open access: yes, 2008
We present a detailed analysis and simulation of solenoidal, magnetically confined electron bombardment ion sources, aimed at molecular beam detection. The aim is to achieve high efficiency for singly ionized species while minimizing multiple ionization.
A. P. Jardine   +9 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations

open access: yesStem Cell Reports, 2019
Summary: Thick-filament sarcomere mutations are a common cause of hypertrophic cardiomyopathy (HCM), a disorder of heart muscle thickening associated with sudden cardiac death and heart failure, with unclear mechanisms.
Rachel Cohn   +10 more
doaj   +1 more source

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