Results 61 to 70 of about 44,849 (251)

A Method for Simultaneous Imaging of Isolated Thick Filaments and Actin Filaments [PDF]

Biophysical Journal, 2014
Actin filaments and thick filaments composed mostly of myosin molecules are nanoscopic structures and often require special imaging techniques for visualization in optical microscope. Actin filaments are 7nm in diameter and therefore require fluorescence labeling to be imaged. Thick filaments isolated from mussel muscles are 70nm in diameter and can be
Kalganov, Albert, Labuda, Aleksander, Rassier, Dilson   +2 more
openaire   +1 more source

Influence of Geometric Design on Mechanical Performance of Auxetic Metastructure

Advanced Engineering Materials, EarlyView.
Strategic geometric reinforcement transforms auxetic performance. This study evaluates 3D‐printed arrowhead metastructures, revealing that a modified design with local ring reinforcement suppresses premature failure to achieve superior energy absorption and structural efficiency.
Muhammad Gulzari, Supharoek Sornsomrit, Muhammad Ayaz Akbar, Stephan Rudykh   +3 more
wiley   +1 more source

Cardiac myosin binding protein C, adrenergic stimulation and cardiac contractility

SA Heart Journal, 2017
Myosin binding protein C remained a perplexing although integral component of the sarcomeric thick filament until the discovery that genetic defects in its corresponding gene is a frequent cause of hypertrophic cardiomyopathy. Basic science investigation
Amsha Ramburan, Lundi Korkie, Johanna C. Moolman-Smook   +2 more
doaj   +1 more source

Ultrastructure of the fertilized egg envelope from Melanotaenia praecox, Melanotaeniidae, Teleostei

Applied Microscopy, 2021
We examined the morphology of fertilized egg and ultrastructures of fertilized egg envelopes of dwarf rainbowfish (Melanotaenia praecox) belong to Melanotaeniidae using light and electron microscopes.
Joon Hyung Sohn, Dong Heui Kim
doaj   +1 more source

In the Thick of It [PDF]

Circulation Research, 2011
In the 20 years since the discovery of the first mutation linked to familial hypertrophic cardiomyopathy (HCM), an astonishing number of mutations affecting numerous sarcomeric proteins have been described. Among the most prevalent of these are mutations that affect thick filament binding proteins, including the myosin essential and regulatory light ...
Samantha P, Harris, Ross G, Lyons, Kristina L, Bezold   +2 more
openaire   +2 more sources

Comparison of Triply Periodic Minimal Surface Energy Absorbers Under Uniaxial Compressive Loading

Advanced Engineering Materials, EarlyView.
This study investigates LCD 3D printed Triply Periodic Minimal Surface (TPMS) structures as mechanical energy absorbers. By comparing various base designs and layered combinations under uniaxial compression, it identifies that a Diamond‐Gyroid sandwich structure offers superior performance.
Sergej Grednev, Noah‐Lean Roschlaub, Anne Jung   +2 more
wiley   +1 more source

Approaches to physical fitness and sports medicine through X-ray diffraction analysis of striated muscle

Journal of Physical Fitness and Sports Medicine, 2016
X-ray diffraction analysis is a method to obtain information about periodically repeated structures. When striated muscle is irradiated with X-ray, many of the reflections and the layer lines, which convey information about molecular structures within ...
Maki Yamaguchi, Shigeru Takemori, Masako Kimura, Naoya Nakahara, Tetsuo Ohno, Toshiko Yamazawa, Shunya Yokomizo, Nobutake Akiyama, Naoto Yagi   +8 more
doaj   +1 more source

Defect Evolution and Mechanical Performance of Fused Filament Fabrication‐Manufactured 17‐4PH Stainless Steel Revealed by X‐Ray Computed Tomography

Advanced Engineering Materials, EarlyView.
X‐ray computed tomography reveals how process‐induced defects evolve from green to sintered states in Fused Filament Fabrication (FFF)‐manufactured 17‐4PH stainless steel. Internal porosity, weakest cross‐sections, and fracture locations show strong correlation with tensile performance, demonstrating the potential of computed tomography (CT)‐based ...
György Ledniczky, Márk Sárközi, Ibolya Zsoldos, Zoltán Weltsch   +3 more
wiley   +1 more source

The sarcomeric protein nebulin: another multifunctional giant in charge of muscle strength optimization

Frontiers in Physiology, 2012
The sliding filament model of the sarcomere was developed more than half a century ago. This model, consisting only of thin and thick filaments, has been successful in explaining many, but not all, features of skeletal muscle.
Coen eOttenheijm, Coen eOttenheijm, Henk eGranzier, Siegfried eLabeit   +3 more
doaj   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source