Results 21 to 30 of about 177,062 (266)

Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M)

Frontiers in Physiology, 2021
α1-microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three original lipocalins when the family first was proposed in 1985.
Jesper Bergwik, Amanda Kristiansson, Amanda Kristiansson, Maria Allhorn, Magnus Gram, Bo Åkerström   +5 more
doaj   +1 more source

PDI Knockdown Inhibits Seizure Activity in Acute Seizure and Chronic Epilepsy Rat Models via S-Nitrosylation-Independent Thiolation on NMDA Receptor

Frontiers in Cellular Neuroscience, 2018
Redox modulation and S-nitrosylation of cysteine residues are the post-translational modifications of N-methyl-D-aspartate receptor (NMDAR) to regulate its functionality. Recently, we have reported that protein disulfide isomerase (PDI) reduces disulfide
A. Ran Jeon, Ji-Eun Kim
doaj   +1 more source

The relationship between thiol-disulfide balance and prostate cancer

Medicine Science, 2020
This study aimed to investigatethe possible association of thiol/disulfidehomeostasiswith prostate-specific antigen levelsin prostate cancer patients and to compare the results with a normal healthy population ofa similar age group for the first time in ...
Ayse Ozdemir, Utku Donem Dilli, Salim Neselioglu, Ozcan Erel   +3 more
doaj   +1 more source

L’évolution des quartiers excentrés de Reims durant l’Antiquité tardive

Gallia
The evolution of Reims/Durocortorum during Late Antiquity reflects a period of profound urban, social, and religious transformation, marked by the contraction of the city’s physical footprint and the reorganization of its spatial and functional dynamics.
Magalie Cavé, Pierre Mathelart, Sandrine Thiol   +2 more
doaj   +1 more source

Biological Mechanisms of S-Nitrosothiol Formation and Degradation: How Is Specificity of S-Nitrosylation Achieved?

Antioxidants, 2021
The modification of protein cysteine residues underlies some of the diverse biological functions of nitric oxide (NO) in physiology and disease. The formation of stable nitrosothiols occurs under biologically relevant conditions and time scales. However,
Christopher M. Massa, Ziping Liu, Sheryse Taylor, Ashley P. Pettit, Marena N. Stakheyeva, Elena Korotkova, Valentina Popova, Elena N. Atochina-Vasserman, Andrew J. Gow   +8 more
doaj   +1 more source

Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine

Metabolites, 2019
The concentration of thiol and thioether metabolites in plasma has diagnostic value in genetic diseases of B-vitamin metabolism linked to methionine utilization. Among these, cysteine/cystine (Cys/CSSC) and glutathione/oxidized glutathione (GSH/GSSG) act
Sidney Behringer, Victoria Wingert, Victor Oria, Anke Schumann, Sarah Grünert, Artur Cieslar-Pobuda, Stefan Kölker, Ann-Kathrin Lederer, Donald W. Jacobsen, Judith Staerk, Oliver Schilling, Ute Spiekerkoetter, Luciana Hannibal   +12 more
doaj   +1 more source

Rapid and Thiol-Specific High-Throughput Assay for Simultaneous Relative Quantification of Total Thiols, Protein Thiols, and Nonprotein Thiols in Cells [PDF]

Analytical Chemistry, 2014
Thiol groups in biological molecules play a significant role in various physiological functions and pathological conditions. Thiols are divided into two major groups: protein thiols and nonprotein thiols. Numerous methods have been reported for thiol assays.
Yang, Yang, Guan, Xiangming
openaire   +2 more sources

Structure–Function Relationship of Novel Tetrakis (Mercapto-Terphenyl)Benzene Cobalt (II) Phthalocyanines: Synthesis and Computational Evaluation

Molecules
This study introduces a newly synthesized Co(II) phthalocyanine complex (Co-Pc, 4) incorporating two (mercapto-terphenyl)thio-dione substituents, along with a detailed exploration of its structural, spectroscopic, and binding characteristics.
Sevil Sener, Nursel Acar-Selcuki
doaj   +1 more source

Binding interaction of a fluoranthene–thiol on gold nanoparticles with β-cyclodextrin and DNA

Journal of Experimental Nanoscience, 2017
In this paper, we report the preparation of a fluoranthene–thiol derivative, the assembly of the compound onto gold nanoparticles, and their binding to β-cyclodextrin and DNA.
S. Eugene Thangaraj, Eva Janet Antony, Sameena Yousuf, P. Mosae Selvakumar, Premnath Dhanaraj, Israel V. M. V. Enoch   +5 more
doaj   +1 more source

Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus Laevis Oocytes

Antioxidants, 2020
Oocytes are postulated to repress the proton pumps (e.g., complex IV) and ATP synthase to safeguard mitochondrial DNA homoplasmy by curtailing superoxide production. Whether the ATP synthase is inhibited is, however, unknown.
James Cobley, Anna Noble, Rachel Bessell, Matthew Guille, Holger Husi   +4 more
doaj   +1 more source