Results 31 to 40 of about 177,062 (266)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Thermally Triggered Interface for Simplified Organic Solar Cells
Advanced Photonics ResearchOrganic photovoltaic (OPV) cells are commonly produced by successive printing of four layers on top of a transparent conducting electrode, with the active layer sandwiched in between interlayers followed by the top electrode.
Suwapat Kongsabay +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Thiol/disulfide homeostasis and oxidant status in children with congenital heart disease
Türk Biyokimya Dergisi, 2021 This article aims to explain the altered oxidative status and thiol/disulfide homeostasis before and after surgery in children with congenital heart disease (CHD).
Sogut Ibrahim +5 more
doaj +1 more source
Thiol Reductases in Deinococcus Bacteria and Roles in Stress Tolerance
Antioxidants, 2022 Deinococcus species possess remarkable tolerance to extreme environmental conditions that generate oxidative damage to macromolecules. Among enzymes fulfilling key functions in metabolism regulation and stress responses, thiol reductases (TRs) harbour ...
Arjan de Groot +3 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Evaluation of Dynamic Disulphide/Thiol Homeostasis in Silica Exposed Workers
Balkan Medical Journal, 2017 Background: Oxidative stress is implicated as one of the main molecular mechanism underlying silicosis. Aims: In this study, our aim was to asses the redox status in occupationally silica-exposed workers, by evaluating the dynamic thiol-disulphide ...
Meşide Gündüzöz +7 more
doaj +1 more source
Comparison of Pre-Operative and Post-Operative Thiol-Disulfide Levels in Acute Abdomen Patients
Journal of Contemporary Medicine, 2023 Aim: To evaluate role of thiol and disulfide homeostasis, a novel marker of oxidative stress, in the follow-up acute abdomen. Material and Method: This prospective study included 107 patients (62 men and 45 women) with a diagnosis of acute abdomen (AA).
Mehmet Berksun Tutan +5 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari +4 more
wiley +1 more source