Results 41 to 50 of about 221,664 (312)

All Hydroxyl-Thiol-Protected Gold Nanoclusters with Near-Neutral Surface Charge

open access: yes, 2021
Hydrophilic gold nanoclusters (Au NCs) whose physical and chemical properties are not susceptible to large changes in pH are greatly desired for diverse applications. Here, we design Au NCs protected by a hydroxyl-thiol ligand (e.g., 1-thioglycerol (TG))
Jianping Xie   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Thiol/disulfide homeostasis and oxidant status in children with congenital heart disease

open access: yesTürk Biyokimya Dergisi, 2021
This article aims to explain the altered oxidative status and thiol/disulfide homeostasis before and after surgery in children with congenital heart disease (CHD).
Sogut Ibrahim   +5 more
doaj   +1 more source

Thiol Reductases in Deinococcus Bacteria and Roles in Stress Tolerance

open access: yesAntioxidants, 2022
Deinococcus species possess remarkable tolerance to extreme environmental conditions that generate oxidative damage to macromolecules. Among enzymes fulfilling key functions in metabolism regulation and stress responses, thiol reductases (TRs) harbour ...
Arjan de Groot   +3 more
doaj   +1 more source

Thiol-Mediated Uptake of a Cysteine-Containing Nanobody for Anticancer Drug Delivery

open access: yes, 2023
The identification of tumor-specific biomarkers is one of the bottlenecks in the development of cancer therapies. Previous work revealed altered surface levels of reduced/oxidized cysteines in many cancers due to overexpression of redox-controlling ...
Helge Ewers (112689)   +10 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Thermally Triggered Interface for Simplified Organic Solar Cells

open access: yesAdvanced Photonics Research
Organic photovoltaic (OPV) cells are commonly produced by successive printing of four layers on top of a transparent conducting electrode, with the active layer sandwiched in between interlayers followed by the top electrode.
Suwapat Kongsabay   +4 more
doaj   +1 more source

Comparison of Pre-Operative and Post-Operative Thiol-Disulfide Levels in Acute Abdomen Patients

open access: yesJournal of Contemporary Medicine, 2023
Aim: To evaluate role of thiol and disulfide homeostasis, a novel marker of oxidative stress, in the follow-up acute abdomen. Material and Method: This prospective study included 107 patients (62 men and 45 women) with a diagnosis of acute abdomen (AA).
Mehmet Berksun Tutan   +5 more
doaj   +1 more source

Thiol-functionalised mesoporous silica-coated magnetite nanoparticles for high efficiency removal and recovery of Hg from water [PDF]

open access: yes, 2012
The preparation and testing of thiol-functionalised silica-coated magnetite nanoparticles (TF-SCMNPs) is described. The characteristics of these particles are assessed at different stages in the production process using X-ray diffraction (XRD ...
Hakami, Othman   +2 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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