Results 51 to 60 of about 221,664 (312)

Quantification of thiols and disulfides [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2014
Disulfide bond formation is a key posttranslational modification, with implications for structure, function and stability of numerous proteins. While disulfide bond formation is a necessary and essential process for many proteins, it is deleterious and disruptive for others.
Winther, Jakob R., Thorpe, Colin
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Evaluation of Dynamic Disulphide/Thiol Homeostasis in Silica Exposed Workers

Balkan Medical Journal, 2017
Background: Oxidative stress is implicated as one of the main molecular mechanism underlying silicosis. Aims: In this study, our aim was to asses the redox status in occupationally silica-exposed workers, by evaluating the dynamic thiol-disulphide ...
Meşide Gündüzöz, Ceylan Bal, Murat Büyükşekerci, Salim Neşelioğlu, Türkan Nadir Öziş, Servet İritaş, Halil Kara, Özcan Erel   +7 more
doaj   +1 more source

Thiol-Reactive Polymers for Titanium Interfaces: Fabrication of Antimicrobial Coatings

, 2019
Infection associated with surgical implants is a major cause of their failure. Often in such cases, the implant has to be removed and replaced, which causes undesirable patient discomfort and complications.
Amitav Sanyal, Tugce Nihal Gevrek, Jayachandran N. Kizhakkedathu, Amitav Sanyal (1547383), Jayachandran N. Kizhakkedathu (645676), Kai Yu, Tugce Nihal Gevrek (2745583), Kai Yu (50223)   +7 more
core   +1 more source

Thiol Disulfide Homeostasis of Pediatric Oncology Patients After the Positron Emission Tomography/Computerized Tomography Imaging: A Cross-Sectional Study [PDF]

, 2021
Aim:Positron emission tomography/computerized tomography (PET/CT) is used for oncologic imaging as hybrid imaging. Pediatric patients are exposed to ionizing radiation when they undergo hybrid medical imaging examinations.
Nilgun Eroglu, Gurses Sahin, Ali Fettah, Emre Capkinoglu, Burcak Bilgin Kurucu, Sule Yesil, Nedim Murat Cuneyt Gulaldi, Ozcan Erel   +7 more
core   +1 more source

Additive Gaussian Process Regression for Predictive Design of High‐Performance, Printable Silicones

Advanced Engineering Materials, EarlyView.
A chemistry‐aware design framework for tuning printable polydimethylsiloxane (PDMS) for vat photopolymerization (VPP) is developed using additive Gaussian process (GP) modeling. Polymer network mechanics informs variable groupings, feasible formulation constraints, and interaction variables.
Roxana Carbonell, Martha Leach, Hongtao Song, Carolyn Seepersad   +3 more
wiley   +1 more source

Acute and persistent Mycobacterium tuberculosis infections depend on the thiol peroxidase TpX.

, 2009
The macrophage is the natural niche of Mycobacterium tuberculosis infection. In order to combat oxidative and nitrosative stresses and persist in macrophages successfully, M. tuberculosis is endowed with a very efficient antioxidant complex.
Hu, Y, Yanmin Hu, Anthony R M Coates, Anthony R. M. Coates, Coates, AR   +4 more
core   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Thiol-Catalyzed Radical Decyanation of Aliphatic Nitriles with Sodium Borohydride

, 2018
Radical decyanation of aliphatic nitriles was achieved in the presence of NaBH4 and a thiol. The reaction proceeds via a radical mechanism involving borane radical anion addition to nitrile to form an iminyl radical, which undergoes carbon–carbon ...
Takuji Kawamoto (1519996), Dennis P. Curran (1330713), Akio Kamimura (1754224), Kyohei Oritani (4922305)   +3 more
core   +1 more source

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

Advanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner, Dhananjeya Kumaar, Giacomo Torti, Killian Keller, Till Zellweger, Florian M. Schenk, Christoph Weilenmann, Daniel Chelladurai, Vara Prasad Jonnalagadda, Ghazi Sarwat Syed, Vanessa Wood, Jürg Leuthold, Alexandros Emboras, Maksym Yarema, Mathieu Luisier   +14 more
wiley   +1 more source