Results 101 to 110 of about 16,205 (199)
Therapeutic Advances in Gastroenterology, 2017 Background: Thiopurines, azathioprine (AZA) and 6-mercaptopurine (6-MP) are common maintenance medications for inflammatory bowel disease (IBD).
Brigitte Moreau +3 more
doaj +1 more source
Beyond the Skin: Can Genetic Variants Predict Crohn's Disease in Psoriasis Patients?
International Journal of Dermatology, Volume 65, Issue 3, Page 425-426, March 2026.
Yuval Ramot
wiley +1 more source
Thiopurine S-methyltransferase activity in Nigerians: phenotypes and activity reference values
BMC Research Notes, 2018 Objectives This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on susceptibility to thiopurine toxicity, and as well generate reference activity values for clinical use.
Ayorinde Adehin, Oluseye O. Bolaji
doaj +1 more source
Journal of General Virology, 2008 The family Flaviviridae comprises positive-strand RNA viral pathogens of humans and livestock with few treatment options. We have previously shown that azathioprine (AZA) has in vitro activity against bovine viral diarrhea virus (BVDV). While the mechanism of inhibition is unknown, AZA and related thiopurine nucleoside analogues have been used as ...
Spencer, Hoover, Rob, Striker
openaire +2 more sources
The Role of Laboratory Tests in Crohn's Disease
Clinical Medicine Insights: Gastroenterology, 2016 In the past, laboratory tests were considered of limited value in Crohn's disease (CD). In the era of biologics, laboratory tests have become essential to evaluate the inflammatory burden of the disease (C-reactive protein, fecal calprotectin) since ...
Maria Cappello +1 more
doaj +1 more source
Personalised medicine, unmet need or business strategy?
, 2013 Personalised medicine is a discipline that integrates pharmaceutical development with existing knowledge about the genetic and phenotypic factors that influence drug response.
Sáinz de la Fuente, G. (Graciela)
core
Drug Design, Development and Therapy, 2019 Ruili Wang,1,2 Baogang Liu,2 Jiapeng Li,1 Jiamin Xu,1 Xiaoling Wang,1 Zhigang Zhao,2 Libo Zhao11Clinical Research Center, Beijing Children’s Hospital, National Center for Children’s Health, Capital Medical University, Beijing, People’s ...
Wang R +6 more
doaj
Development of a Scalable Pharmacogenomic Clinical Decision Support Service [PDF]
, 2014 Advances in sequencing technology are making genomic data more accessible within the healthcare environment. Published pharmacogenetic guidelines attempt to provide a clinical context for specific genomic variants; however, the actual implementation to ...
Brownstein, Catherine +7 more
core
, 2014 Purpose of review: Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression.
Burroughs, AK +2 more
core
Thiopurine Methyltransferase Activity and Thiopurine Metabolites in Inflammatory Bowel Disease [PDF]
Crohn's & Colitis 360, 2020 openaire +2 more sources