Pharmacogenetic studies of thiopurines : focus on thiopurine methyltransferase
, 2005 Pharmacogenetics represents the study ofvariability in drug response due to genetic variations. The thiopurines (6-mercaptopurine, 6-thioguanine and azathioprine) are prodrugs which require metabolic transformation to exert effect. Thiopurines are used in inflammatory bowel disease, as maintenance treatment of childhood acute lymphoblastic leukaemia ...
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Acquired Immunodeficiency in Newborn Following Intrauterine Exposure to Thiopurines for Treatment of Inflammatory Bowel Disease. [PDF]
ACG Case Rep JMorand S +7 more
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Azathioprine-Associated Acute Pancreatitis Followed by a Probable Autoimmune Hepatitis Flare After Thiopurine Withdrawal: A Case Report. [PDF]
CureusMarfo E, Oladoyin V, Liu J.
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Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease. [PDF]
, 2009 Burger, D. C., Florin, T. H. J.
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Development and Validation of a Sensitive Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Simultaneous Quantification of Thiopurine Nucleotides in Human Red Blood Cells. [PDF]
CureusSingh M, Kaushal S, Gupta K, Sood A.
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Pharmacogenetic Analysis of TPMT and NUDT15 in a European Pediatric Cohort with IBD and Autoimmune Diseases: Frequency Data and Clinical Relevance. [PDF]
Genes (Basel)Pau A +10 more
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Vedolizumab in inflammatory bowel disease: pharmacokinetics and the role of immunomodulator co-therapy. [PDF]
Ther Adv GastroenterolPudipeddi A +6 more
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