Results 111 to 120 of about 6,219 (200)
Sequential group trial to determine gastrointestinal site of absorption and systemic exposure of azathioprine [PDF]
, 2000 Azathioprine (AZA) is used in the treatment of patients with refractory inflammatory bowel disease; however, its use is limited because of systemic toxicity associated with long-term use.
Abell, Thomas +7 more
core +1 more source
Journal of General Virology, 2008 The family Flaviviridae comprises positive-strand RNA viral pathogens of humans and livestock with few treatment options. We have previously shown that azathioprine (AZA) has in vitro activity against bovine viral diarrhea virus (BVDV). While the mechanism of inhibition is unknown, AZA and related thiopurine nucleoside analogues have been used as ...
Spencer, Hoover, Rob, Striker
openaire +2 more sources
Development of a Scalable Pharmacogenomic Clinical Decision Support Service [PDF]
, 2014 Advances in sequencing technology are making genomic data more accessible within the healthcare environment. Published pharmacogenetic guidelines attempt to provide a clinical context for specific genomic variants; however, the actual implementation to ...
Brownstein, Catherine +7 more
core
Pharmacogenetics – individualized treatment of genetic disorders [PDF]
, 2011 Farmakogenetika je grana znanosti koja proučava povezanost genotipa sa različitom reakcijom na terapiju nekim lijekovima. Potencijal farmakogenetike je velik jer će dobiveni rezultati istraživanja omogućiti i olakšati individualizirano liječenje ...
Biluš, Mirna
core +2 more sources
Normal Ranges of Thiopurine Methyltransferase Activity Do Not Affect Thioguanine Nucleotide Concentrations With Azathioprine Therapy in Inflammatory Bowel Disease. [PDF]
Crohns Colitis 360, 2020 Jonason DE +4 more
europepmc +1 more source
Personalised medicine, unmet need or business strategy?
, 2013 Personalised medicine is a discipline that integrates pharmaceutical development with existing knowledge about the genetic and phenotypic factors that influence drug response.
Sáinz de la Fuente, G. (Graciela)
core
UEG Week 2025 Moderated Posters
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley +1 more source
HaematologicaAllopurinol can be used in maintenance therapy (MT) for pediatric acute lymphoblastic leukemia (ALL) to mitigate hepatic toxicity in patients with skewed 6- mercaptopurine metabolism.
Jonatan Källström +10 more
doaj +1 more source
Elevated liver enzymes in inflammatory bowel disease: the role and safety of infliximab [PDF]
, 2016 BACKGROUND: Abnormal liver enzymes are frequently encountered in inflammatory bowel disease (IBD) patients. Infliximab has been implicated in inducing drug-induced liver injury, autoimmune hepatitis or reactivation of hepatitis B virus.
Burroughs, AK +9 more
core