Results 71 to 80 of about 5,819 (161)
Autopsy and Case Reports, 2017 The standard therapy for some autoimmune diseases consists of a combination of corticosteroids and thiopurines. In non-responders to thiopurine drugs, the measurement of the metabolites of azathioprine, 6-thioguanine, and 6-methylmercaptopurine, can be a
Ana Luiza Vilar Guedes +7 more
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Beyond the Skin: Can Genetic Variants Predict Crohn's Disease in Psoriasis Patients?
International Journal of Dermatology, Volume 65, Issue 3, Page 425-426, March 2026.
Yuval Ramot
wiley +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2016 Background and Aims. Thiopurines are used in the treatment of Crohn’s disease (CD) and thiopurine S-methyltransferase (TPMT) activity can guide thiopurine dosing to avoid adverse events.
Amine Benmassaoud +6 more
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Journal of General Virology, 2008 The family Flaviviridae comprises positive-strand RNA viral pathogens of humans and livestock with few treatment options. We have previously shown that azathioprine (AZA) has in vitro activity against bovine viral diarrhea virus (BVDV). While the mechanism of inhibition is unknown, AZA and related thiopurine nucleoside analogues have been used as ...
Spencer, Hoover, Rob, Striker
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Managing Ulcerative Colitis – The Guidelines and Beyond [PDF]
European Medical Journal Gastroenterology, 2013 Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the use of 5-ASA, corticosteroids, thiopurines, cyclosporine, and anti-TNFα therapies.
Mitchell RKL Lie +1 more
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Thiopurine Methyltransferase Activity and Thiopurine Metabolites in Inflammatory Bowel Disease [PDF]
Crohn's & Colitis 360, 2020 openaire +2 more sources
Pharmacogenetic studies of thiopurines : focus on thiopurine methyltransferase
, 2005 Pharmacogenetics represents the study ofvariability in drug response due to genetic variations. The thiopurines (6-mercaptopurine, 6-thioguanine and azathioprine) are prodrugs which require metabolic transformation to exert effect. Thiopurines are used in inflammatory bowel disease, as maintenance treatment of childhood acute lymphoblastic leukaemia ...
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Optimal management of steroid-dependent ulcerative colitis
Clinical and Experimental Gastroenterology, 2015 Hafiz M Waqas Khan,1 Faisal Mehmood,1 Nabeel Khan2 1Department of Medicine, King Edward Medical University, Lahore, Pakistan; 2Section of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia VA Medical Center ...
Khan HMW, Mehmood F, Khan N
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