Results 231 to 240 of about 169,438 (276)

Redundant and Flexible Electron Transfer Pathways Underlie MsrPQ‐Mediated Repair of Oxidized Periplasmic Proteins

open access: yesMolecular Microbiology, Volume 125, Issue 6, Page 493-505, June 2026.
This study investigates in vivo the role of the flavin reductase Fre as an electron supplier to the periplasmic methionine sulfoxide reductase system MsrPQ. ABSTRACT The MsrPQ system is essential for the repair of oxidized methionine residues in periplasmic proteins, ensuring bacterial resistance to oxidative stress and envelope integrity.
Laurent Loiseau, Benjamin Ezraty
wiley   +1 more source

LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3597-3615, June 2026.
LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro   +4 more
wiley   +1 more source

Deciphering photosynthetic protein networks: a crosslinking‐MS strategy for studying functional thylakoid membranes

open access: yesThe Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Photosynthesis, which sustains life on Earth, depends on organized and yet adaptable protein assemblies embedded in specialized membranes known as thylakoids. Understanding how these complexes interact and reorganize within functional photosynthetic membranes is essential to reveal the molecular basis of energy conversion in cells.
Nicolas Frances   +4 more
wiley   +1 more source

Transcription of photosynthetic genes in the plant chloroplast: lessons from bacteria

open access: yesThe Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY The RNA polymerase that transcribes photosynthetic genes in the plant chloroplast is the largest known transcription enzyme across all domains of life, comprising 21 subunits of bacterial and eukaryotic origin. Recent structural analyses revealed that the core polymerase, inherited from the cyanobacterial ancestor of the chloroplast, is encased
Jessica Moon   +5 more
wiley   +1 more source

Prevention of Weight Regain After GLP1RA Cessation With Oral TIX100

open access: yes
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5339-5342, June 2026.
SeongHo Jo   +5 more
wiley   +1 more source

Overexpression of cytosolic NADP‐malic enzyme 1 from the common ice plant enhances water‐deficit and high‐light stress tolerance by modulating water‐use efficiency and flavonoid biosynthesis

open access: yesThe Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Innovative strategies are essential to enhance crop resilience against drought and heat stress intensified by climate change. Crassulacean acid metabolism (CAM) is a specialized photosynthetic pathway that improves water‐use efficiency (WUE) by shifting CO2 fixation to the nighttime. The common ice plant (Mesembryanthemum crystallinum) utilizes
Sang Hun Kim   +5 more
wiley   +1 more source

Development of Immunoelectron Microscopy for VASN Detection Using Multiple Models and Identification of VASN as a Key Regulator of Mitochondrial Homeostasis in Hepatocellular Carcinoma Cells

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
We developed an optimized immunoelectron microscopy method (IEM‐VASN) for precise VASN localization, rigorously validated in both gene‐edited cells and knockout mice. Application of this method uncovered distinct mitochondrial enrichment of VASN.
Xiaojing Cheng   +11 more
wiley   +1 more source

The thioredoxin antioxidant system

Free Radical Biology and Medicine, 2014
The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thioredoxin, is a key antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance.
Jun Lu, Arne Holmgren
exaly   +3 more sources

Insights into the Specificity of Thioredoxin Reductase−Thioredoxin Interactions. A Structural and Functional Investigation of the Yeast Thioredoxin System

open access: yesBiochemistry, 2010
The enzymatic activity of thioredoxin reductase enzymes is endowed by at least two redox centers: a flavin and a dithiol/disulfide CXXC motif. The interaction between thioredoxin reductase and thioredoxin is generally species-specific, but the molecular aspects related to this phenomenon remain elusive.
Oliveira, Marcos A.   +5 more
core   +5 more sources

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