Results 231 to 240 of about 17,263,040 (272)

Trypanosomal MICOS Is Assembled on Non‐Respiring Mitochondrial Crista Precursors and Associates With Two Integral Microproteins

Molecular Microbiology, Volume 126, Issue 4, Page 396-411, October 2026.
The mitochondrial membrane‐shaping machinery MICOS is assembled surprisingly early during the life cycle of Trypanosoma brucei, before the mitochondrion acquires its mature architecture or full respiratory capacity. Our study also identifies two previously uncharacterized proteins associated with MICOS, providing new insight into the early organization
Michala Boudová, Teresa Wagner, Tomáš Bílý, Martina Tesařová, Corinna Benz, Hassan Hashimi   +5 more
wiley   +1 more source

Two proteins co‐expressed with photosynthetic regulators affect photosynthetic dynamics linked to changes in thylakoid pigment content and composition

Plant Biology, Volume 28, Issue 6, Page 1796-1812, October 2026.
Two factors identified by co‐expression analysis of photosynthetic regulators are described, which are involved in thylakoid pigment content and composition and, through their function, shape the dynamics of NPQ. Abstract Rapid fluctuations in light intensity require swift regulatory adjustments of photosynthesis. Although the major plant regulators of
J.‐M. Keller, F. Dinc, E. Kaiser, A. Zupok, B. A. Morris, T. von Bismarck, V. Correa Galvis, W. Thiele, D. M. Kramer, P. Jahns, M. A. Schöttler, U. Armbruster   +11 more
wiley   +1 more source

Disulphide maintenance systems and proteostasis. [PDF]

Philos Trans R Soc Lond B Biol Sci
West JD.
europepmc   +1 more source

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The thioredoxin antioxidant system

Free Radical Biology and Medicine, 2014
The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thioredoxin, is a key antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance.
Arne Holmgren, Jun Lu
exaly   +3 more sources

PLANT THIOREDOXIN SYSTEMS REVISITED [PDF]

Annual Review of Plant Biology, 2000
▪ Abstract  Thioredoxins, the ubiquitous small proteins with a redox active disulfide bridge, are important regulatory elements in plant metabolism. Initially recognized as regulatory proteins in the reversible light activation of key photosynthetic enzymes, they have subsequently been found in the cytoplasm and in mitochondria.
P Schürmann
exaly   +4 more sources

The plant thioredoxin system

Cellular and Molecular Life Sciences, 2005
Thioredoxins are small proteins catalyzing thiol-disulfide interchange and are involved in the regulation of the redox environment of the cell. In plants, the thioredoxin system is particularly complex since at least 20 thioredoxin isoforms are found in the plant model Arabidopsis thaliana.
Gelhaye, Éric, Rouhier, Nicolas, Navrot, Nicolas, Jacquot, Jean-Pierre   +3 more
openaire   +5 more sources

The thioredoxin system in cancer

Seminars in Cancer Biology, 2006
Thioredoxin (Trx), NADPH and thioredoxin reductase (TrxR) comprise a thioredoxin system which exists in nearly all living cells. It functions in thiol-dependent thiol-disulfide exchange reactions crucial to control of the reduced intracellular redox environment, cellular growth, defense against oxidative stress or control of apoptosis and has multi ...
Elias S J, Arnér, Arne, Holmgren
openaire   +2 more sources

Thioredoxin in the cardiovascular system

Journal of Molecular Medicine, 2006
The thioredoxin (TRX) system (TRX, TRX reductase, and NADPH) is a ubiquitous thiol oxidoreductase system that regulates cellular reduction/oxidation (redox) status. The impairment of cell redox state alters multiple cell pathways, which may contribute to the pathogenesis of cardiovascular disorders including hypertension, atherosclerosis, and heart ...
Cameron J, World, Hideyuki, Yamawaki, Bradford C, Berk   +2 more
openaire   +2 more sources

The Thioredoxin System — From Science to Clinic

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Stephan, Gromer, Sabine, Urig, Katja, Becker   +2 more
openaire   +2 more sources

Targeting the Thioredoxin System for Cancer Therapy

Trends in Pharmacological Sciences, 2017
Thioredoxin (Trx) and thioredoxin reductase (TrxR) are essential components of the Trx system which plays pivotal roles in regulating multiple cellular redox signaling pathways. In recent years TrxR/Trx have been increasingly recognized as an important modulator of tumor development, and hence targeting TrxR/Trx is a promising strategy for cancer ...
Junmin Zhang, Ruijuan Liu, Jianguo Fang
exaly   +3 more sources