Results 41 to 50 of about 17,263,040 (272)

Redox Systems in Botrytis cinerea: Impact on Development and Virulence

Molecular Plant-Microbe Interactions, 2014
The thioredoxin system is of great importance for maintenance of cellular redox homeostasis. Here, we show that it has a severe influence on virulence of Botrytis cinerea, demonstrating that redox processes are important for host-pathogen interactions in
Anne Viefhues, Jens Heller, Nora Temme, Paul Tudzynski   +3 more
doaj   +1 more source

Novel potential interacting partners of fibronectin in spontaneous animal model of interstitial cystitis [PDF]

, 2012
Feline idiopathic cystitis (FIC) is the only spontaneous animal model for human interstitial cystitis (IC), as both possess a distinctive chronical and relapsing character. Underlying pathomechanisms of both diseases are not clearly established yet.
Amann, Barbara, Hauck Stefanie M., Kerstin N. Euler, Barbara Amann, Dorsch Roswitha, Euler, K.N., Cornelia A Deeg, Dorsch, Roswitha, Roswitha Dorsch, Kerstin N Euler, Euler Kerstin N., Deeg Cornelia A., Amann Barbara, Treutlein, Gudrun, Stefanie M Hauck, Stefanie M. Hauck, Deeg, Cornelia A., Treutlein Gudrun, Hauck, Stefanie M., Euler, Kerstin N., Cornelia A. Deeg, Amann, B., Hartmann, Katrin, Hartmann Katrin, Hauck, S.M., Hartmann, K., Katrin Hartmann, Treutlein, G., Gudrun Treutlein, Deeg, C.A., Dorsch, R.   +30 more
core   +2 more sources

Thioredoxin–thioredoxin reductase – a system that has come of age [PDF]

European Journal of Biochemistry, 2000
‹12 000 protein having a redoxactive disulfide; thioredoxin was the name assigned to thisprotein [4]. It was shown that thioredoxin was reduced bythioredoxin reductase in a NADPH-dependent reaction and thatin its dithiol form, thioredoxin served as the reductant ofribonucleotides via a ribonucleotide reductase.
openaire   +3 more sources

JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. [PDF]

PLoS ONE, 2010
The selenoenzyme thioredoxin reductase 1 has a complex role relating to cell growth. It is induced as a component of the cellular response to potentially mutagenic oxidants, but also appears to provide growth advantages to transformed cells by inhibiting
Kornelia Edes, Pamela Cassidy, Paul J Shami, Philip J Moos   +3 more
doaj   +1 more source

Thioredoxin and Glutaredoxin Systems [PDF]

, 2019
This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description ...
Zaffagnini, Mirko, Jacquot, Jean-Pierre
openaire   +3 more sources

A multi-centre study on the role of the thioredoxin system in breast cancer cell proliferation

Бюллетень сибирской медицины, 2018
Redox proteins (thioredoxin, glutaredoxin) are key macromolecules capable of modulating intracellular processes. This determines research choices in the field of redox-dependent cell proliferation management.
E. V. Shakhristova, E. A. Stepovaya, O. L. Nosareva, L. S. Litvinova, D. A. Skuratovskaya, E. V. Rudikov, A. A. Sadykova, V. V. Novitsky   +7 more
doaj   +1 more source

Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury. [PDF]

PLoS ONE, 2017
Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of atmospheric oxygen (hyperoxia), used clinically to treat tissue hypoxia in premature newborns, is known to elicit oxidative ...
Benjamin J Forred, Darwin R Daugaard, Brianna K Titus, Ryan R Wood, Miranda J Floen, Michelle L Booze, Peter F Vitiello   +6 more
doaj   +1 more source

Cloning of thioredoxin h reductase and characterization of the thioredoxin reductase–thioredoxin h system from wheat [PDF]

Biochemical Journal, 2002
Thioredoxins h are ubiquitous proteins reduced by NADPH— thioredoxin reductase (NTR). They are able to reduce disulphides in target proteins. In monocots, thioredoxins h accumulate at high level in seeds and show a predominant localization in the nucleus of seed cells.
Pérez Ruiz, Juan Manuel, Cejudo Fernández, Francisco Javier, Serrato Recio, Antonio Jesús   +2 more
openaire   +4 more sources

Long-Term Treatment with Low-Level Arsenite Induces Aberrant Proliferation and Migration via Redox Rebalance in Human Urothelial Cells

Cells
Chronic exposure to arsenic via drinking water can induce bladder cancer in humans. Nevertheless, there is little knowledge about the precise mechanisms of this.
Xiangli Yan, Qing Zhou, Shuhua Xi, Peiyu Jin   +3 more
doaj   +1 more source

Natural product based inhibitors of the thioredoxin–thioredoxin reductase system

Org. Biomol. Chem., 2004
Spiroketal naphthodecalins are readily assembled by Barton's base mediated Ullmann binaphthyl ether coupling, Dakin reactions and hypervalent iodine spirocyclization. The core structures can be further diversified by enone addition and Stille coupling reactions.
Wipf, Peter, Lynch, Stephen M., Birmingham, Anne, Tamayo Castillo, Giselle, Jiménez, Allan, Campos, Nefertiti, Powis, Garth   +6 more
openaire   +4 more sources