Results 31 to 40 of about 17,263,040 (272)

The thioredoxin reductase system of mycoplasmas [PDF]

Microbiology, 1997
Representative species of the Mollicutes possess a thioredoxin reductase system (NTS) composed of a low-molecular-mass thioredoxin (TRX) and NADPH-binding thioredoxin reductase (NTR). The TRXs of Mycoplasma pneumoniae and M. capricolum have molecular masses of 11.2 and 12 kDa, respectively, and are stable at 90 °C for 10 min.
G, Ben-Menachem, R, Himmelreich, R, Herrmann, Y, Aharonowitz, S, Rottem   +4 more
openaire   +2 more sources

The role of thioredoxin proteins in Mycobacterium tuberculosis probed by proteome-wide target profiling

Biochemistry and Biophysics Reports, 2023
Mycobacterium tuberculosis encounters diverse microenvironments, including oxidative assault (ROS and RNS), when it attempts to establish itself within its human host.
Sapna Sugandhi, Vyankatesh Rajmane, Khushman Taunk, Sushama Jadhav, Vijay Nema, Srikanth Rapole, Shekhar C. Mande   +6 more
doaj   +1 more source

The role of thioredoxin reductases in brain development [PDF]

, 2008
The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin reductases in brain using mice with nervous system (NS ...
Jonna Soerensen, Schmidt, Jörg, Soerensen, Jonna, Markus Brielmeier, Schweizer, Ulrich, Schmahl, W., Schweizer, U., Jakupoglu, Cemile, Brielmeier, Markus, Heike Beck, Schmahl, Wolfgang W., Marcus Conrad, Conrad, M., Jörg Schmidt, Brielmeier, M., Förster, Heidi, Conrad, Marcus, Förster, H., Beck, H., Wolfgang Schmahl, Beck, Heike, Jakupoglu, C., Cemile Jakupoglu, Soerensen, J., Heidi Förster, Ulrich Schweizer, Schmidt, J.   +26 more
core   +2 more sources

Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. [PDF]

, 2009
The malarial parasite Plasmodium falciparum possesses a functional thioredoxin and glutathione system comprising the dithiol-containing redox proteins thioredoxin (Trx) and glutaredoxin (Grx), as well as plasmoredoxin (Plrx), which is exclusively found ...
Sturm, Nicole, Becker Katja, Koncarevic, Sasa, Forchhammer, Karl, Mailu, Boniface M., Rahlfs, Stefan, Katja Becker, Deponte, Marcel, Koncarevic Sasa, Becker, Katja, Sturm Nicole, Mailu Boniface M., Marcel Deponte, Deponte Marcel, Jortzik, Esther, Stefan Rahlfs, Jortzik Esther, Esther Jortzik, Karl Forchhammer, Nicole Sturm, Forchhammer Karl, Boniface M Mailu, Sasa Koncarevic, Rahlfs Stefan   +23 more
core   +2 more sources

Tissue Distribution and Activity of Thioredoxin Reductase in Pancreatic Carcinoma [PDF]

Middle East Journal of Cancer, 2019
Background: Thioredoxin, NADPH, and thioredoxin reductase form the thioredoxinsystem which exists in all living cells. Oxidants have a major role in cancer pathogenesis;therefore, it is necessary to study the role of redox-active compounds such as ...
Faezeh Sadrabadi Haghighi, Mohsen Aliakbarian, Alireza Khooei, Seyed Isaac Hashemy   +3 more
doaj   +1 more source

Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer

Cells, 2019
We have demonstrated previously that melatonin attenuates hepatotoxicity triggered by high doses of (−)-epigallocatechin-3-gallate (EGCG) in mice.
Lingyun Zhang, Yufeng He, Ximing Wu, Guangshan Zhao, Ke Zhang, Chung S. Yang, Russel J. Reiter, Jinsong Zhang   +7 more
doaj   +1 more source

Giardia lamblia: missing evidence for a canonical thioredoxin system [PDF]

, 2017
The microaerophilic protozoan parasite Giardia lamblia occurs globally and causes dysentery in humans and animals. Since it is very sensitive to oxygen and reactive oxygen species, G.
Müller, Norbert, David Leitsch, Leitsch, David, Norbert Müller, Rout, Samuel, Adrian Hehl, Lundström-Stadelmann, Britta, Britta Lundström-Stadelmann, Vreni Balmer, Hehl, Adrian, Samuel Rout, Balmer, Vreni   +11 more
core   +2 more sources

Fluorogenic probes for thioredoxin reductase activity

Results in Chemistry, 2021
The thioredoxin system is vital in maintaining the cellular redox state and is implicated in various cancers and other diseases. It comprises of thioredoxin reductase, thioredoxin and NADPH.
Tendai J. Mafireyi, Jorge O. Escobedo, Robert M. Strongin   +2 more
doaj   +1 more source

Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice

Redox Biology, 2016
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea.
Ruixia Dong, Dongxu Wang, Xiaoxiao Wang, Ke Zhang, Pingping Chen, Chung S. Yang, Jinsong Zhang   +6 more
doaj   +1 more source

The Antioxidant System of the Respiratory Tract. The Intracellular Antioxidant Protection in the Respiratory Tract (Part 4)

Zdorovʹe Rebenka, 2016
In the literature review, the current data about the thioredoxin system in the functioning of the intracellular antioxidant protection in the respiratory tract are outlined. The details of thioredoxin-dependent oxidation reaction are described.
A.E. Abaturov, A.P. Volosovets, T.P. Borysova   +2 more
doaj   +1 more source