Results 1 to 10 of about 320,403 (261)

Defects in Glutathione System in an Animal Model of Amyotrophic Lateral Sclerosis [PDF]

Antioxidants, 2023
Amyotrophic lateral sclerosis (ALS) is a progredient neurodegenerative disease characterized by a degeneration of the first and second motor neurons.
Franziska T. Wunsch, Nils Metzler-Nolte, Carsten Theiss, Veronika Matschke   +3 more
doaj   +2 more sources

Pantothenic Acid Derivatives Modulate Oxidative Stress and Hepatic Fibrosis in Bile Duct Ligation-Induced Cholestatic Liver Injury [PDF]

Pathophysiology
Background/Objectives: Inflammation and oxidative stress are key factors contributing to the initiation and progression of liver fibrosis in chronic obstructive cholestasis.
Dmitry S. Semenovich, Polina A. Abramicheva, Ljubava D. Zorova, Andrey V. Elchaninov, Maria A. Kozlova, David A. Areshidze, Nadezda V. Andrianova, Nina P. Kanunnikova, Andrey G. Moiseenok, Irina B. Pevzner, Egor Y. Plotnikov, Dmitry B. Zorov   +11 more
doaj   +2 more sources

The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes. [PDF]

Antioxidants (Basel), 2023
Cassier-Chauvat C, Marceau F, Farci S, Ouchane S, Chauvat F.   +4 more
europepmc   +2 more sources

Evidence that glutathione and the glutathione system efficiently recycle 1-cys sulfiredoxin in vivo. [PDF]

Antioxid Redox Signal, 2015
Aims: Typical 2-Cys peroxiredoxins (2-Cys Prxs) are Cys peroxidases that undergo inactivation by hyperoxidation of the catalytic Cys, a modification reversed by ATP-dependent reduction by sulfiredoxin (Srx).
Boukhenouna S, Mazon H, Branlant G, Jacob C, Toledano MB, Rahuel-Clermont S.   +5 more
europepmc   +4 more sources

The glutathione system and the related thiol network in Caenorhabditis elegans. [PDF]

Redox Biol, 2019
Ferguson GD, Bridge WJ.
europepmc   +2 more sources

Long-term results of the enzyme glutation system activity in experimental ovarian cancer

Journal of Education, Health and Sport, 2022
The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova, R. Yeromenko, I. Savytskyi, T. Alexandryna, L. Sarakhan   +4 more
doaj   +1 more source

Forms of pseudotuberculosis progression in children and the impact of lipid peroxidation activation and antioxidant system imbalance on their development

Журнал инфектологии, 2021
The objective is to compare clinical symptoms, lipid peroxidation indicators, the state of the antioxidant system and assess their impact on the severity and progression of pseudotuberculosis in children.Materials and methods.
A. P. Pomogaeva, O. L. Nosareva, E. A. Stepovaya, T. V. Zhavoronok, E. V. Shakhristova, E. I. Krasnova, A. V. Vasyunin   +6 more
doaj   +1 more source

Transcriptional changes of proteins of the thioredoxin and glutathione systems in Acanthamoeba spp. under oxidative stress – an RNA approach

Parasite, 2022
The thioredoxin (Trx) and the glutathione (GSH) systems represent important antioxidant systems in cells and in particular thioredoxin reductase (TrxR) has been shown to constitute a promising drug target in parasites.
Köhsler Martina, Leitsch David, Loufouma Mbouaka Alvie, Wekerle Maximilian, Walochnik Julia   +4 more
doaj   +1 more source

The state of the glutathione system of the cerebral of rats under the conditions of energy drink consumption

Біологія тварин, 2023
The paper presents the results of studies of the energy drink influence on the state of the glutathione system of the rat brain. Energy tonics belong to a group of drinks containing a large number of active components that are able to stimulate the ...
N. I. Lytvyniuk, H. M. Ersteniuk
doaj   +1 more source

Effect of new water-soluble phenolic antioxidants on the activity of Nrf2-driven enzymes, glutathione system, and Nrf2 translocation into the nucleus

Сибирский научный медицинский журнал, 2020
Understanding the role of reactive oxygen and nitrogen species in eustress (redox balance) and distress (oxidative stress) development poses new challenges for biomedical scientists and pharmacologists in the search for compounds that can not only have a
E. B. Menshchikova, N. K. Zenkov, P. M. Kozhin, A. V. Chechushkov, V. S. Pavlov, L. P. Romakh, M. V. Khrapova, A. E. Serykh, O. B. Gritsyk, N. V. Kandalintseva   +9 more
doaj   +1 more source