Results 11 to 20 of about 320,403 (261)

Changes in glutathione system and lipid peroxidation in rat blood during the first hour after chlorpyrifos exposure [PDF]

The Ukrainian Biochemical Journal, 2015
Chlorpyrifos (CPF) is a highly toxic organophosphate compound, widely used as an active substance of many insecticides. Along with the anticholinesterase action, CPF may affect other biochemical mechanisms, particularly through disrupting pro- and ...
V. P. Rosalovsky, S. V. Grabovska, Yu. T. Salyha   +2 more
doaj   +1 more source

The Efficacy of a Peptide Product from the Pituitary Gland of Rangifer tarandus as an Antioxidant Agent Under the Combined Effects of Light Desynchronosis and Depriming Toxicant

Антибиотики и Химиотерапия, 2021
The possibility of using methods for determining the oxidative status of an organism (enzymatic and non-enzymatic links of the cellular antioxidant system) to assess the antioxidant properties of peptides of the pituitary gland of the reindeer (Rangifer ...
E. G. Batotsyrenova, V. A. Kashuro, A. V. Sharabanov, V. K. Kozlov, A. L. Kovalenko   +4 more
doaj   +1 more source

Optimizing the Intensive Care Treatment of Delirium in Patients with 1,4-butanediol Intoxication

Общая реаниматология, 2020
The aim of the study is to explore the best intensive care strategies for acute 1,4-butanediol poisoning complicated by post-intoxication delirium.Materials and methods.
A. G. Sinenchenko, A. N. Lodyagin, B. V. Butotsyrenov   +2 more
doaj   +1 more source

Parameters of the glutathione system and thioredoxin in blood plasma and ascites and GSTP1 Ile105Val gene polymorphism as factors of resistance to platinum-containing chemotherapy in ovarian cancer patients

Бюллетень сибирской медицины, 2021
Background. Chemotherapy is one of the main types of treatment in ovarian cancer. Standard first-line treatment includes platinum drugs. Every fifth patient develops chemoresistance after platinum-containing first line therapy. Glutathione detoxification
D. R. Dolgova, T. R. Gening, T. V. Abakumova, S. O. Gening, I. I. Antoneeva, A. Yu. Fedotova   +5 more
doaj   +1 more source

Assessment of the glutathione system and the biomolecules oxidation products contribution to the state of free radical homeostasis in women of two ethnic groups with insomnia

Сибирский научный медицинский журнал, 2023
Own and literature data showed a change in the free radical oxidation products and indicators of the glutathione system concentration in menopausal women with insomnia. The change in the studied parameters depended on the ethnicity of the patients.
N. V. Semenova, A. S. Lesnaya, I. M. Madaeva, O. A. Nikitina, L. I. Kolesnikova   +4 more
doaj   +1 more source

Metabolic Remodeling during Long-Lasting Cultivation of the Endomyces magnusii Yeast on Oxidative and Fermentative Substrates

Microorganisms, 2020
In this study, we evaluated the metabolic profile of the aerobic microorganism of Endomyces magnusii with a complete respiration chain and well-developed mitochondria system during long-lasting cultivation.
Elena P. Isakova, Irina N. Matushkina, Tatyana N. Popova, Darya I. Dergacheva, Natalya N. Gessler, Olga I. Klein, Anastasya V. Semenikhina, Yulia I. Deryabina, Nicola La Porta, Nils-Eric L. Saris   +9 more
doaj   +1 more source

The glutathione/glutathione-related enzyme system in reproduction

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2000
Contains fulltext : 179382.pdf (Publisher’s version ) (Open Access)
Knapen, M.F.C.M., Zusterzeel, P.L.M., Peters, W.H.M., Steegers, E.A.P.   +3 more
openaire   +5 more sources

Glutathione-Related Enzymes and Proteins: A Review

Molecules, 2023
The tripeptide glutathione is found in all eukaryotic cells, and due to the compartmentalization of biochemical processes, its synthesis takes place exclusively in the cytosol.
Janka Vašková, Ladislav Kočan, Ladislav Vaško, Pál Perjési   +3 more
doaj   +1 more source

Molecular mechanisms of the effects of N-ethylmaleimide and 1,4-dithioerythritol on regulation of apoptosis in P19 cells under hypoxia

Бюллетень сибирской медицины, 2020
Relevance. Impairment of apoptosis regulation in P19 cells is correlated with generation of oxidative stress. Under hypoxia, changes in mitochondrial functions occur, which may exacerbate oxidative stress in the tumor cell.
O. L. Nosareva, D. S. Orlov, E. V. Shakhristova, E. A. Stepovaya   +3 more
doaj   +1 more source

Effects of Panthenol and N-Acetylcysteine on Changes in the Redox State of Brain Mitochondria under Oxidative Stress In Vitro

Antioxidants, 2021
The glutathione system in the mitochondria of the brain plays an important role in maintaining the redox balance and thiol–disulfide homeostasis, whose violations are the important component of the biochemical shifts in neurodegenerative diseases ...
Dmitry S. Semenovich, Egor Yu. Plotnikov, Oksana V. Titko, Elena P. Lukiyenko, Nina P. Kanunnikova   +4 more
doaj   +1 more source