Results 21 to 30 of about 17,263,040 (272)

The thioredoxin h system: potential applications

Biotechnology Advances, 2005
The thioredoxin h system has the specific capability to reduce intramolecular disulfide bonds of proteins, thereby modifying their tertiary structure. It is involved in many processes: in the activation or deactivation of enzymes and enzyme inhibitors and in the germination process. This system can be used to improve the breadmaking quality of wheat by
Joudrier, Philippe, Gautier, Marie Francoise, de Lamotte, Frédéric, Kobrehel, Karoly   +3 more
openaire   +5 more sources

Thioredoxin System Protein Expression Is Associated with Poor Clinical Outcome in Adult and Paediatric Gliomas and Medulloblastomas. [PDF]

Mol Neurobiol, 2020
The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox homeostasis. Protein expression of Trx system family members has been assessed in various cancers and linked to various clinicopathological variables, disease ...
Yao A, Storr SJ, Al-Hadyan K, Rahman R, Smith S, Grundy R, Paine S, Martin SG.   +7 more
europepmc   +2 more sources

Thioredoxin System Protein Expression in Carcinomas of the Pancreas, Distal Bile Duct, and Ampulla in the United Kingdom. [PDF]

Diseases
Background: Poor survival outcomes in periampullary cancer highlight the need for improvement in biomarkers and the development of novel therapies.
Al-Hadyan KS, Storr SJ, Zaitoun AM, Lobo DN, Martin SG.   +4 more
europepmc   +2 more sources

The over expression of thioredoxin during malignancies [PDF]

Reviews in Clinical Medicine, 2014
Thioredoxin system comprised of thiorexin and NADPH dependent thiorexin reductase, is responsible for redox regulation of cells by controlling the apoptosis, proliferation and other vital processes of cells.
Shahaboddin Shabani, Navid Nourizadeh, Mohammadsaleh Soltankhah   +2 more
doaj   +3 more sources

Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment. [PDF]

Antioxidants (Basel), 2020
Chronic myeloid leukaemia (CML) is currently treated with inhibitors of the CML specific oncoprotein, bcr-abl. While this strategy is initially successful, drug resistance can become a problem.
Clapper E, Wang S, Raninga PV, Di Trapani G, Tonissen KF.   +4 more
europepmc   +2 more sources

Improved Tolerance of Lactiplantibacillus plantarum in the Presence of Acid by the Heterologous Expression of trxA from Oenococcus oeni

Fermentation, 2022
Oenococcus oeni is the main microorganism that undergoes malolactic fermentation (MLF) in the winemaking industry due to its excellent adaptability to harsh wine environments.
Longxiang Liu, Xinyu Yu, Ming Wu, Keying Zhang, Shuai Shang, Shuai Peng, Weiyu Song   +6 more
doaj   +1 more source

Cellular Responses Required for Oxidative Stress Tolerance of the Necrotrophic Fungus Alternaria alternata, Causal Agent of Pear Black Spot

Microorganisms, 2022
To establish successful infections in host plants, pathogenic fungi must sense and respond to an array of stresses, such as oxidative stress. In this study, we systematically analyzed the effects of 30 mM H2O2 treatment on reactive oxygen species (ROS ...
Miao Zhang, Yandong Zhang, Yongcai Li, Yang Bi, Renyan Mao, Yangyang Yang, Qianqian Jiang, Dov Prusky   +7 more
doaj   +1 more source

Transcriptional changes of proteins of the thioredoxin and glutathione systems in Acanthamoeba spp. under oxidative stress – an RNA approach

Parasite, 2022
The thioredoxin (Trx) and the glutathione (GSH) systems represent important antioxidant systems in cells and in particular thioredoxin reductase (TrxR) has been shown to constitute a promising drug target in parasites.
Köhsler Martina, Leitsch David, Loufouma Mbouaka Alvie, Wekerle Maximilian, Walochnik Julia   +4 more
doaj   +1 more source

The Thioredoxin System of Helicobacter pylori [PDF]

Journal of Biological Chemistry, 2000
This paper describes the purification of thioredoxin reductase (TR) and the characterization, purification, and cloning of thioredoxin (Trx) from Helicobacter pylori. Purification, amino acid sequence analysis, and molecular cloning of the gene encoding thioredoxin revealed that it is a 12-kDa protein which possesses the conserved redox active motif ...
H J, Windle, A, Fox, D, Ní Eidhin, D, Kelleher   +3 more
openaire   +4 more sources

Degradation of somatomedins by the thioredoxin system [PDF]

FEBS Letters, 1985
Insulin Degradation Thioredoxin Insulin‐like growth factor I Insulin‐like growth factor II
Enberg, Gösta, Holmgren, Arne
openaire   +2 more sources