Results 11 to 20 of about 8,698 (205)
Recent Advances in Isatin-Thiazole Hybrids: Synthesis, Structural Design, and Biological Application. [PDF]
Chem BiodiversABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Andrade IMG +4 more
europepmc +2 more sources
1-(Cycloheptylidene)thiosemicarbazide [PDF]
IUCrData, 2019 The asymmetric unit of the title compound, C8H15N3S, contains two independent molecules. In both molecules, the seven-membered cycloheptane ring adopts a chair conformation. An intramolecular N—H...N hydrogen bond is observed in both molecules, forming S(5) graph-set motifs.
Mulveer Singh +4 more
openaire +2 more sources
Molecules, 2023 Chromatographic methods, apart from in silico ones, are commonly used rapid techniques for the evaluation of certain properties of biologically active compounds used for their prediction of pharmacokinetic processes.
Marek Studziński +4 more
doaj +1 more source
Coumarinyl Thiosemicarbazides as Antimicrobial Agents [PDF]
Pharmaceutical Chemistry Journal, 2018 A two series of coumarinyl thiosemicarbazides were synthesized. One series derived from coumarin core substituted in position 7 and another from coumarin core substituted in position 4. All compounds were obtained in reaction of corresponding hydrazide and various isothiocyanates.
Molnar, Maja +2 more
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THE ANTI-NEOPLASTIC ACTIVITY OF THE COORDINATIVE COMPOUNDS, THIOSEMICARBAZIDE DERIVATES
Arta Medica, 2023 Background. Thiosemicarbazide derivates are considered potential compounds of the antitumor drugs, with a large spectrum of biological properties. The aim of the research was to reflect the actual progress in studies on thiosemicarbazide derivates ...
Valeriana Pantea, Evelina Lesnic
doaj +1 more source
Designing the morphology of PbS nanoparticles through a single source precursor method
Journal of Saudi Chemical Society, 2017 The synthesis and characterization of lead sulphide nanoparticles using complexes as single sources of both lead and sulphur are reported. A cubic phase of galena perfectly matched all synthesized nanoparticles confirming that no secondary product was ...
Kalenga Pierre Mubiayi +3 more
doaj +1 more source
Platinum(II), palladium(II) and gold(III) complexes containing 1,1,4-trisubstituted thiosemicarbazide dianion ligands [PDF]
, 2003 Reactions of cis-[PtCl₂(PPh₃)₂] or [PdCl₂(PPh₃)₂] with Ph₂N---NHC(S)NHPh and excess triethylamine, in refluxing methanol gave the complexes [M{SC(=NPh)NNPh₂}(PPh₃)₂] containing thiosemicarbazide dianion ligands.
Henderson, William +1 more
core +2 more sources
Data in Brief, 2019 New compound, namely (Z)-1-[4-(trifluoromethyl)benzylidene]thiosemicarbazide was successfully synthesized using thiosemicarbazide with 4-(trifluoromethyl)-benzaldehyde in ethanol solution.
Uwaisulqarni M. Osman +5 more
doaj +1 more source
Molecules, 2020 We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and ...
Bushra Adalat +8 more
doaj +1 more source
Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Compounds containing thiadiazole moiety are cognized to possess with variety of clinical and therapeutic activity. Finding a suitable drug target for newly synthesized compounds remain a major bottle neck in current high throughout ...
Rohan J. Meshram +4 more
doaj +1 more source