Results 71 to 80 of about 8,698 (205)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Three novel series of N-methylsulfonylindole derivatives 3a&b, 4a–e, and 5a–e were synthesised. Different biological activities of the synthesised compounds were studied.
John N. Philoppes +5 more
doaj +1 more source
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]
, 2019 New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone +8 more
core +2 more sources
Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents
Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar +6 more
wiley +1 more source
Recent synthetic strategies of medicinally important imidazothiadiazoles
Journal of Saudi Chemical Society, 2023 Imidazothiadiazole is a fundamental fused heterocyclic compound containing imidazole and thiadiazole ring systems. This versatile framework has significant applications in pharmaceutical chemistry and also possessed a remarkable biological profile.
Tooba Jabeen +6 more
doaj +1 more source
Synthesis and reactions of some new thieno[2,3-b]quinolines and pyrrolylthienoquinolines [PDF]
, 2010 8-Benzylidene-3-cyano-4-phenyl-5,6,7,8-tetrahydroquinolin-2(1H)thione (2) was synthesized and used asstarting material for the synthesis of poly fused heterocycles e.g thienoquinolines, oxadiazolylthienoquinolines and ...
Gaber, Abd El-Aal, Geies, Ahmed
core
Unprecedented Pt(II) complex of an asymmetric 2,6-diacetylpyridine bis(4N-substituted thiosemicarbazone) ligand [PDF]
, 2013 NOTICE: this is the author’s version of a work that was accepted for publication in Inorganic Chemistry Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Matesanz, Ana I., Souza, Pilar
core +2 more sources
Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares +4 more
wiley +1 more source
Synthesis and evaluation of fluorimetric and colorimetric chemosensors for anions based on (oligo)thienyl-thiosemicarbazones [PDF]
, 2012 A family of heterocyclic thiosemicarbazone dyes (3a-d) containing thienyl groups has been synthesized, characterized and their chromo-fluorogenic response in acetonitrile in the presence of selected anions studied.
Agostini +89 more
core +2 more sources
Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa +9 more
wiley +1 more source
International Journal of Electrochemical Science, 2012 Novel corrosion inhibitor as a green chemical product namely derivative, 2-amino 5-oleyl-1,3,4-thiadiazol (AOT) was synthesized by cyclization of oleic acid. The new corrosion inhibitor was characterized by FT-IR and NMR spectroscopical methods.
Sutiana Junaedi +4 more
doaj +1 more source