Results 91 to 100 of about 2,239,305 (281)

A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis [PDF]

open access: yes, 2015
We have developed a modular software system that enables researchers to monitor and control chemical reactions via the internet, using any device from any location in the world.
Battilocchio, C   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Resonantly Forced Inhomogeneous Reaction-Diffusion Systems

open access: yes, 2000
The dynamics of spatiotemporal patterns in oscillatory reaction-diffusion systems subject to periodic forcing with a spatially random forcing amplitude field are investigated.
C. J. Hemming, Gáspár V., R. Kapral
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Hopf Bifurcation in a Three-Component Reaction-Diffusion System with a Chemoattraction

open access: yesAbstract and Applied Analysis, 2013
We consider a three-component reaction-diffusion system with a chemoattraction. The purpose of this work is to analyze the chemotactic effects due to the gradient of the chemotactic sensitivity and the shape of the interface.
YoonMee Ham, Sang-Gu Lee, Quoc Phong Vu
doaj   +1 more source

On the Formation of CO2 and Other Interstellar Ices

open access: yes, 2011
We investigate the formation and evolution of interstellar dust-grain ices under dark-cloud conditions, with a particular emphasis on CO2. We use a three-phase model (gas/surface/mantle) to simulate the coupled gas--grain chemistry, allowing the ...
Garrod, Robin T., Pauly, Tyler
core   +1 more source

Phosphosulfonic acid, an efficient solid acid catalyst for the one-pot preparation of 14-aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxo-octahydro-xanthenes under solvent-free conditions [PDF]

open access: yes, 2013
An expeditious procedure for the synthesis of 14- aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxo-octahydro-xanthenes through one-pot pseudo three component condensation of β-naphthol or dimedone with various aryl aldehydes is described.
Kiasat Reza Ali   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

ZrOCl2·8H2O: An efficient and recyclable catalyst for the three-component synthesis of amidoalkyl naphthols under solvent-free conditions

open access: yesJournal of Saudi Chemical Society, 2016
An efficient synthesis of amidoalkyl naphthols from the reaction of β-naphthol and various aromatic aldehydes and amides using ZrOCl2·8H2O, an environmentally friendly catalyst under a thermal solvent-free green procedure is described.
S. Sheik Mansoor   +3 more
doaj   +1 more source

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