Results 11 to 20 of about 18,631,052 (336)
Airway branching morphogenesis in three dimensional culture [PDF]
Respiratory Research, 2010 Background Lungs develop from the fetal digestive tract where epithelium invades the vascular rich stroma in a process called branching morphogenesis.
Gudjonsson Thorarinn +5 more
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Three-Dimensional Culture of Mouse Eyecups
Methods in molecular biology, 2019 Retinal neurons and glia in the adult vertebrate retina are differentiated from multipotent retinal progenitors in the eyecups under the regulation of intrinsic and extrinsic factors, but the molecular mechanism underlying the process is partially ...
Raven Diacou, Punita Bhansali, Wei Liu
semanticscholar +3 more sources
, 2022 Exosomes derived from mesenchymal stem cells (MSCs) have been proven to exhibit great potentials in spinal cord injury (SCI) therapy. However, conventional two-dimensional (2D) culture will inevitably lead to the loss of stemness of MSCs, which ...
Xiaofeng Wang (119575) +11 more
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Regulating tension in three-dimensional culture environments [PDF]
Experimental Cell Research, 2013 The processes of development, repair, and remodeling of virtually all tissues and organs, are dependent upon mechanical signals including external loading, cell-generated tension, and tissue stiffness.
M. Kural, K. Billiar
semanticscholar +4 more sources
Three-dimensional culture of tumor cells (Review). [PDF]
Oncol LettWhile conventional two-dimensional (2D) cell cultures and animal models have been cornerstone technologies in cancer research, they possess limitations in replicating human tumor pathophysiology. Notably, 2D models fail to capture key tissue-level architecture and cell-cell interactions, whereas animal models are often constrained by species-specific ...
Du S, Yang J, Li H, Men S, Xu D, Wang H.
europepmc +4 more sources
Three-Dimensional Cell Cultures in Toxicology [PDF]
Biotechnology and Genetic Engineering Reviews, 2009 Toxicity testing with animals is expensive, ethically controversial, and not always predictive of the human response. Cell-based assays are regarded as an alternative. However, conventional two-dimensional cell cultures do not reproduce the tissue architecture in vivo, and do not forecast organ-specific toxicity.
Francesco, Pampaloni, Ernst, Stelzer
openaire +2 more sources
Modeling lymphangiogenesis in a three-dimensional culture system [PDF]
Nature Methods, 2008 A lack of appropriate in vitro models of three-dimensional lymph vessel growth hampers the study of lymphangiogenesis. We developed a lymphatic ring assay--a potent, reproducible and quantifiable three-dimensional culture system for lymphatic endothelial cells that reproduces spreading of endothelial cells from a pre-existing vessel, cell proliferation,
Bruyere, Françoise +12 more
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Establishment of A Three-Dimensional Culture Condition for The U266 Cell Line Based on Peripheral Blood Plasma-Derived Fibrin Gels [PDF]
Cell Journal, 2023 Objective: The study of pathophysiology as well as cellular and molecular aspects of diseases, especially cancer,requires appropriate disease models. In vitro three-dimensional (3D) structures attracted more attention to recapitulatediseases rather than ...
Mahshid Jomehpour +4 more
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Journal of Cell Biology, 1997 In a recently developed human breast cancer model, treatment of tumor cells in a 3-dimensional culture with inhibitory β1-integrin antibody or its Fab fragments led to a striking morphological and functional reversion to a normal phenotype. A stimulatory
V. Weaver +6 more
semanticscholar +1 more source
Three‐dimensional culture models to study drug resistance in breast cancer
Biotechnology and Bioengineering, 2020 Despite recent advances in breast cancer treatment, drug resistance frequently presents as a challenge, contributing to a higher risk of relapse and decreased overall survival rate.
M. F. Fisher, Shreyas S. Rao
semanticscholar +1 more source