Results 101 to 110 of about 111,761,861 (179)

Clinicopathological features in membranous nephropathy with cancer: A retrospective single-center study and literature review

open access: yesThe International Journal of Biological Markers, 2019
Background: Membranous nephropathy is the most common glomerular disease related to malignancy. However, it is difficult to distinguish between true malignancy-related membranous nephropathy and idiopathic membranous nephropathy coincident with cancer ...
Dan Zhang   +5 more
doaj   +1 more source

The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy

open access: yes, 2019
Idiopathicmembranous nephropathy(IMN) is an autoimmune glomerular disease with unknown etiology. Current studies have shown that phospholipase A2 receptor(PLA2R) and thrombospondin type-1 domain 7 A(THSD7A) are closely related to the pathogenesis of IMN.
LI Jun, WANG Yan-yan, CHENG Hong
core  

Islet vascularity in wild-type and thrombospondin-1 deficient animals.

open access: yes, 2013
Micrographs of blood vessel-stained (Bandeiraea simplicifolia; red) pancreas form one-year-old wild-type and thrombospondin-1 deficient mice (A–B). Vascular density in 10–12 week-old, 16-week-old and one-year-old wild-type and thrombospondin-1 deficient ...
Johan Olerud (302167)   +4 more
core   +1 more source

Expression and significance of phospholipase A2 receptor and thrombospondin type-1 domain 7A in idiopathic membranous nephropathy

open access: yes, 2019
Objective To investigate expression and significance of phospholipase A2 receptor(PLA2 R) and thrombospondin type-1 domain 7 A(THSD7 A) in idiopathic membranous nephropathy(IMN).
WANG Li-hua   +6 more
core  

Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens.

open access: yes, 2007
Experimental malaria vaccines based on two sporozoite stage candidate antigens of Plasmodium falciparum, the circumsporozoite protein (CSP) and thrombospondin-related adhesive protein (TRAP), have undergone clinical trials of efficacy.
Sutherland, Colin J   +9 more
core   +1 more source

The significance of anti-PLA2R antibody in the diagnosis and treatment of primary membranous nephropathy

open access: yesLinchuang shenzangbing zazhi, 2019
Primary membranous nephropathy(PMN) is a glomerulus-specific autoimmune disorder mainly caused by challenge of autoantibodies against the recently discovered antigens located on podocytes, such as the M-type phospholipase A2 receptor(PLA2R), the ...
XU Dong-mei, LIU Yi-peng
doaj  

Autocrine regulation of T cell motility by calreticulin-thrombospondin-1 interaction

open access: yes, 2005
The mechanisms regulating T lymphocyte migration within the extracellular matrix are not understood. We show in this study that the thrombospondin-1 binding site of calreticulin, spanning aa 19-32, is a major triggering factor for T cell motility and ...
Ivanoff, Anna,   +2 more
core  

Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway.

open access: yes, 2006
Thrombospondin-1, a multi-modular matrix protein is able to interact with a variety of matrix proteins and cell-surface receptors. Thus it is multifunctional.
Dedieu, S.   +13 more
core   +1 more source

Molecular immunopharmacology of traditional Chinese medicine–derived compounds in membranous nephropathy: mechanistic insights into immune aging and kidney essence deficiency

open access: yesFrontiers in Immunology
Membranous nephropathy (MN) is a prototypical immune-mediated glomerular disease characterized by the formation of autoantibodies targeting podocyte antigens, deposition of subepithelial immune complexes, and activation of complement pathways leading to ...
Sichao Ma   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy