Results 111 to 120 of about 111,761,865 (181)

Molecular immunopharmacology of traditional Chinese medicine–derived compounds in membranous nephropathy: mechanistic insights into immune aging and kidney essence deficiency

Frontiers in Immunology
Membranous nephropathy (MN) is a prototypical immune-mediated glomerular disease characterized by the formation of autoantibodies targeting podocyte antigens, deposition of subepithelial immune complexes, and activation of complement pathways leading to ...
Sichao Ma, Mingxin Chang, Yabin Cui, Hong ‘an Wang, Yunfan Liu, Shoulin Zhang   +5 more
doaj   +1 more source

Purification of an insect derived recombinant human ADAMTS-1 reveals novel gelatin (type I collagen) degrading activities

, 2006
ADAMTS-1 (A Disintegrin And Metalloprotease with ThromboSpondin repeats) is a member of a family of secreted proteolytic enzymes with a complex modular structure.
McKie, Norman, Birch, Mark A, Lind, Thomas   +2 more
core   +1 more source

Thrombospondin type-1 domain-containing 7A—a new player in membranous nephropathy [PDF]

Nature Reviews Nephrology, 2014
openaire   +1 more source

Computational Insights into the Structure and Epitope locations for Two Idiopathic Membranous Nephropathy Antigens: Phospholipase A ₂ Receptor and the Thrombospondin Type‐1 Containing Domain 7A and Design of Antigen Binding Proteins

The FASEB Journal, 2018
The use of non‐specific treatment options in autoimmune therapy today unfortunately causes patients to be prone to other infections. This non‐specific therapy suppresses the entire patient's immunes system also making it harder to fight of basic infections.
openaire   +1 more source

Clinicopathological characteristics of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy

Clinicopathological characteristics of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy
Thrombospondin type 1 domain-containing 7A (THSD7A) is a recently identified target antigen of idiopathic membranous nephropathy (iMN). The clinicopathological characteristics of THSD7A-associated MN are poorly characterised due to low prevalence among MN patients.
openaire   +1 more source

SUN-030 PHOSPHOLIPASE A2 RECEPTOR AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING 7A IN MALIGNANCY MEMBRANOUS NEPHROPATHY [PDF]

Kidney International Reports, 2019
C. Zhang, M. Zhang, D. Chen, Q. Ren, W. Xu, C. Zeng, W. Qin, Z.H. Liu   +7 more
openaire   +1 more source

Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

, 2016
The α2δ proteins are auxiliary subunits of voltage-gated calcium channels, and influence their trafficking and biophysical properties. The α2δ ligand gabapentin interacts with α2δ-1, and inhibits calcium channel trafficking.
Ho, S, Page, KM, Dolphin, AC, Kadurin, I, Lana, B, Nieto-Rostro, M   +5 more
core  

Activation of podocyte-specific MC5R signaling by melanocortin therapy protects against THSD7A-associated membranous nephropathy

Translation
Jing Liu, Yan Ge, Lance Dworkin, Rujun Gong   +3 more
doaj   +1 more source

SP147PREVALENCE OF M−TYPE PHOSPHOLIPASE A2 RECEPTOR (PLA2R) AND THROMBOSPONDIN TYPE−1 DOMAIN−CONTAINING 7A (THSD7A) IN THE GLOMERULAR DEPOSITS OF JAPANESE MEMBRANOUS NEPHROPATHY [PDF]

Nephrology Dialysis Transplantation, 2016
Norifumi Hayashi, Yuki Matsui, Junko Imura, Keiji Fujimoto, Hiroki Adachi, Hideki Yamaya, Hitoshi Yokoyama   +6 more
openaire   +1 more source

Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type-1 domain-containing 7A in glioblastoma

Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type-1 domain-containing 7A in glioblastoma
博士論文要旨Abstract 以下に掲載：Cancer Medicine 9(11) pp.3904-3917 2020. John Wiley & Sons Ltd.
openaire   +3 more sources